Phototherapy and Chemotherapy in Vitiligo Treatment

The document reviewed the use of phototherapy in treating vitiligo, a skin disorder characterized by white macules. Vitiligo affects 0.5-4% of the global population, often appearing before age 20. The exact cause is unknown, but theories include immune system alterations, nerve-related chemical damage, and melanocyte structural issues. Treatment relies on melanocyte reservoirs, primarily in hair follicles, lesion edges, and depigmented epidermis. Initial treatments involve topical therapies or localized phototherapy, with systemic therapies or phototherapy for more extensive cases. Surgical options are considered for refractory and stable lesions. The review summarized existing studies and evidence supporting phototherapy's effectiveness in vitiligo treatment.