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Lack of sleep in mice leads to prostatitis by reducing certain hormones and activating an inflammatory pathway, which can be temporarily fixed with normal sleep.

Certain genes and pathways are linked to the production of finer and denser wool in Hetian sheep.

Hair follicle stem cells reduced hair loss and inflammation in mice with a condition similar to human alopecia.

Understanding genes and hormones is crucial for managing male puberty and sex development disorders.

DSDs are birth conditions causing unusual sex development, managed with personalized care and sometimes surgery, but still lack a standard treatment approach.

DHT, a testosterone byproduct, causes male pattern baldness.

Changes in gut bacteria can contribute to the development of Polycystic Ovary Syndrome (PCOS), affecting metabolism, immunity, and causing inflammation. Treatments may involve adjusting these factors.

Infertile men are more likely to produce sperm with abnormal chromosome numbers, which can affect pregnancy success and embryo health.

Oestrogens are key for bone growth during puberty in both boys and girls.

Estrogens are key for bone growth spurts in both boys and girls and affect growth into adulthood.

Steroidogenic isoenzymes may help improve treatments for common hair loss.

AGA treatments like minoxidil and LLLLT are safe and effective for gender minority patients.

A protein found in safflower seeds can stimulate hair growth and speed up wound healing in mice.

Mesenchymal stromal cells may help treat severe COVID-19, but more research is needed to confirm their effectiveness.

Animal models, especially mice, are essential for advancing hair loss research and treatment.

High levels of male hormones, insulin resistance, and obesity are closely linked and worsen polycystic ovary syndrome, but more research is needed to improve treatments.

Neuroactive steroids could become safe, effective treatments with more understanding of their complex brain actions and metabolism.

Selective Androgen Receptor Modulators (SARMs) are drugs that can control the effects of androgens in different tissues, potentially having fewer side effects and promising for treating various conditions.

The document concludes that using LC-MS/MS for measuring androgens is more accurate than older methods, but it needs careful validation and standardized references to be most effective.

The review concludes that more research is needed to better improve the health outcomes for people with Polycystic Ovarian Syndrome.

A 36-year-old person with a female appearance but male chromosomes was diagnosed with a rare enzyme deficiency affecting sexual development.

Sebaceous glands play a key role in skin health, immunity, and various skin diseases.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Fat cells are important for healthy skin, hair growth, and healing, and changes in these cells can affect skin conditions and aging.

Eating a Mediterranean diet and taking certain supplements may improve symptoms of PCOS.

The Brazilian Society of Dermatology agrees that oral isotretinoin is effective for acne and other skin conditions, and it's safe when monitored, but more research is needed on dosing and duration.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

Blocking 5α-reductase can harm memory and brain structure, and increase harmful brain changes in male mice used for Alzheimer's disease research.

The document concludes that for hair and feather growth, it's better to target the environment around stem cells than the cells themselves.

The document summarizes medical findings on topics like heart rhythm treatment, sleep apnea therapy, and various health conditions and treatments.