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Women with more 3α,17β-androstanediol glucuronide compared to sex hormone binding globulin are more likely to have female pattern baldness.

Measuring androstanediol glucuronide in blood is useful for assessing and tracking treatment in women with excessive hair growth.

Cyproterone acetate effectively reduced hair growth in hirsute patients by lowering androgen levels and altering androgen metabolism.

People with hair loss may have different levels of certain hormones due to changes in hormone processing.

We need to learn more about 5α-reductases and neuroactive steroids to safely make drugs targeting these enzymes.

Men using hair loss drugs like finasteride may experience sexual side effects like erectile dysfunction, but it's unclear who will be affected and when. Treating depression and sexual symptoms is suggested, as these men often have higher rates of both. More research is needed to understand why these side effects occur.

Hair loss drugs like finasteride may cause lasting sexual and mood side effects, and more research is needed to understand these risks.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

5-alpha reductase inhibitors, like finasteride and dutasteride, may cause depression, but more research is needed to understand why.

Combination therapy for 9+ months maintains symptom improvements after stopping alpha-blockers or finasteride.

Finasteride reduces new brain cells in male mice, possibly causing depression.

Finasteride may increase depression by reducing brain cell growth.

Finasteride may protect brain and improve behavior in rats with liver failure.

A brain-produced steroid causes increased scratching in mice with a skin condition similar to eczema.

PSA levels are higher in women with PCOS, but FAI is a more accurate marker for diagnosis.

Pregnancy reduces anxiety in rats, but finasteride reverses this effect.

The testosterone patch and gel are both effective, but they have different absorption patterns and effects on hormone levels.

Sarcoptes scabiei infection causes significant health and behavior changes in wombats.

Daughters of women with PCOS generally experience normal puberty but may have more body hair and different body fat distribution.

Adipose tissue shows promise for hair regrowth, but more research is needed to confirm best practices and effectiveness.

Cocaine impairs male sexual behavior and alters testosterone metabolism in the brain.

Drugs targeting the Androgen Receptor are effective for treating prostate cancer and other androgen-related conditions.

Testosterone's muscle-building effects do not require its conversion to DHT.

17α-estradiol is a safe estrogen that might protect the brain and doesn't cause feminization, needing more research for treating brain diseases.

Mice lacking steroid 5α-reductase 2 show less aggression and better impulse control.

Saw palmetto extract may help with hair loss and acne but needs more research on safety and long-term effects.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

Hormonal interactions, especially involving DHT and estrogen, play a key role in BPH development and treatment.

Gut microbes significantly affect brain steroid levels.

Galenic lotions can effectively treat different patterns of hair thinning in men and women.