April 2024 in “bioRxiv (Cold Spring Harbor Laboratory)” GRK2 is essential for healthy hair follicle function, and its absence can lead to hair loss and cysts.
The research found how certain drugs and polymers form stable complexes, which could help develop new pharmaceutical forms.
September 2019 in “Journal of Investigative Dermatology” Frog skin cells need the protein desmoplakin for proper development and cell layer formation.
OCT can effectively screen and diagnose various medical conditions non-invasively.
1533 citations,
October 2008 in “Endocrine reviews” Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.
158 citations,
August 2011 in “Reviews in endocrine and metabolic disorders” Vitamin D and its receptor regulate skin functions like cell growth, immunity, hair cycle, and tumor prevention.
28 citations,
March 2013 in “Stem cells” Certain human skin cells marked by CD44 and ALDH are rich in stem cells capable of long-term skin renewal.
September 2014 in “Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE” OCT can effectively examine and reveal details about human hair and scalp conditions.
56 citations,
April 2012 in “Developmental biology” Sostdc1 controls the size and number of hair and mammary gland structures.
May 2022 in “Frontiers in Cell and Developmental Biology” miR-29a-5p prevents the formation of early hair structures by targeting a gene important for hair growth and is regulated by a complex network involving lncRNA627.1.
16 citations,
July 2020 in “Advanced functional materials” 3D cell-derived matrices improve tissue regeneration and disease modeling.
2 citations,
April 2021 in “International Journal of Molecular Sciences” The study concluded that changing the culture conditions can cause sika deer skin cells to switch from a flat to a 3D pattern, which is important for creating hair follicles.
January 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Newly born mesenchymal cells quickly spread out in response to tissue tension during early development.
Researchers developed a method to create artificial hair follicles that may help with hair loss treatment and research.
48 citations,
December 2004 in “Differentiation” Tooth papilla cells can help regenerate hair follicles and grow hair.
34 citations,
May 2021 in “Journal of Nanobiotechnology” The 3D electrospun fibrous sponge is promising for tissue repair and healing diabetic wounds.
31 citations,
February 2021 in “Experimental Dermatology” Skin organoids are a promising new model for studying human skin development and testing treatments.
29 citations,
April 2020 in “Biomolecules” The 3D scaffold helped maintain hair cell traits and could improve hair loss treatments.
17 citations,
December 2019 in “Stem Cell Research & Therapy” Grouping certain skin cells together activates a growth pathway that helps create new hair follicles.
12 citations,
June 2006 in “Anais Brasileiros de Dermatologia” The study found average numbers for different types of hair follicles in the scalp and observed differences between men and women, suggesting reasons for more common hair shedding in women.
8 citations,
January 2019 in “Experimental Dermatology” The 3D skin model is better for hair growth research and testing treatments.
3 citations,
December 2013 in “Journal of Dermatology” Scanning electron microscopy revealed four distinct hair root shapes in alopecia areata, suggesting a less invasive diagnostic method.
February 2024 in “Biomedical materials” Scientists created a lab-grown hair follicle model that behaves like real hair and could improve hair loss treatment research.
November 2023 in “Frontiers in veterinary science” The study provides insights into hair growth mechanisms in yaks.
835 citations,
October 2008 in “Nature Genetics” Lgr5 is a marker for active, long-lasting stem cells in mouse hair follicles.
228 citations,
November 2012 in “Trends in Neurosciences” Nerves are crucial for the regeneration of various body parts in many animals.
77 citations,
August 2020 in “Cell” Muscles and nerves that cause goosebumps also help control hair growth.
70 citations,
November 1984 in “Cell & tissue research/Cell and tissue research” Vitamin D3 affects cell differentiation in specific skin areas.
62 citations,
February 2016 in “ACS Applied Materials & Interfaces” Technique creates 3D cell spheroids for hair-follicle regeneration.
42 citations,
January 2017 in “Stem cells international” Adding hyaluronic acid helps create larger artificial hair follicles in the lab.