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Dihydrotestosterone treatment can help penis growth in boys with 5α-reductase deficiency but doesn't fully normalize size after puberty.

5α-reductase inhibitors, like finasteride and dutasteride, effectively treat BPH, male baldness, and hirsutism, with potential for acne and prostate cancer prevention.

Certain drugs that block specific enzymes can help treat prostate diseases.

Finasteride and dutasteride may help prevent hair loss but could cause side effects like sexual dysfunction and psychological issues.

Finasteride effectively treats hair loss and enlarged prostate in men, with mild side effects.

New compounds show promise for treating hair loss, enlarged prostate, and prostate cancer, with some being more effective and having different side effects than current treatments.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

5-alpha reductase inhibitors can cause sexual side effects like erectile dysfunction and reduced sexual desire, sometimes lasting after stopping the drug.

Dutasteride caused more penile tissue changes than finasteride, possibly increasing erectile dysfunction risk.

The document concludes that the risk of sexual side effects from 5-alpha-reductase inhibitors is low and often temporary, but more research is needed on potential permanent effects.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

5-alpha reductase inhibitors, like finasteride and dutasteride, may cause depression, but more research is needed to understand why.

5α-reductase inhibitors can cause sexual problems, higher risk of aggressive prostate cancer, and depression.

Selective non-steroidal inhibitors of 5α-reductase type 1 can help treat DHT-related disorders.

5α-reductase inhibitors like finasteride may not be effective or safe for transgender individuals, and more research is needed.

Long-term use of dutasteride for enlarged prostate may worsen blood sugar, cholesterol, and erectile dysfunction.

Dutasteride is linked to a higher chance of sexual dysfunction, especially in younger males and the elderly.

Oral dutasteride can potentially treat frontal fibrosing alopecia in postmenopausal women, with some patients showing disease arrest and hair regrowth.

Compounds from the plant Mammea siamensis may help treat hair loss.

New steroid compounds effectively inhibit 5α-reductase and may treat hair loss.

No effective treatment for frontal fibrosing alopecia was found, but oral 5-alpha-reductase inhibitors had the best response; for lichen planopilaris, topical corticosteroids were commonly used but had a high relapse rate.

5 alpha-reductase inhibitors like finasteride may lower prostate cancer risk and improve cancer screening.

Early diagnosis and combination therapy, especially with finasteride and dutasteride, are key to managing Frontal Fibrosing Alopecia effectively.

Combining minoxidil with dutasteride and microneedling is more effective for female pattern hair loss than just dutasteride and microneedling.

Dutasteride can reduce night-time urination but it doesn't improve sleep quality.

Dutasteride may help stabilize Frontal Fibrosing Alopecia, but more research is needed.

Dutasteride is more effective than finasteride for hair growth with similar side effects.

Frontal Fibrosing Alopecia's cause is unclear, affects mainly postmenopausal women, and current treatments focus on stopping hair loss rather than regrowth.

Heredity and hormones cause common hair loss, and topical minoxidil is the first recommended treatment.

Dermatologists recommend oral dutasteride for male hair loss, low-dose oral minoxidil for female hair loss, and a multidisciplinary approach for young patients, with caution during pregnancy.