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This review discusses various risk factors and potential therapeutic interventions for PCOS but reports no new clinical results.

This study generated FGF5-knockout Dorper sheep using the CRISPR/Cas9 system, resulting in significantly increased fine-wool and active hair-follicle density, and explored downstream signaling pathways for potential applications in androgen alopecia treatment.

This review details the expression and diverse functions of melatonin receptors in non-neural tissues and reports no new clinical findings, emphasizing their potential as therapeutic targets across various physiological and pathological processes.

This article reviews the mechanisms by which minoxidil stimulates hair growth and reports no new clinical findings.

This article reviews the clinical complications and increased mortality risks associated with Cushing's syndrome but does not present new clinical data; it emphasizes the need for prompt treatment to mitigate these risks.

This review discusses the complex etiology of polycystic ovary syndrome (PCOS), highlighting its association with insulin resistance and hyperandrogenism, but reports no clinical findings; the authors suggest further investigation of the pathophysiological mechanisms.

This review discusses recent strategies targeting the neuroactive steroid biosynthetic pathway to enhance neurosteroidogenesis, highlighting their potential benefits for neurodegenerative and neuropsychiatric diseases, but reports no new clinical findings.

In this study, researchers found that in late pregnancy, the neuroactive progesterone metabolite allopregnanolone inhibits HPA axis responses to immune challenges via an opioid-mediated mechanism.

This article outlines the clinical features, evaluation, and treatment strategies for androgen excess in polycystic ovary syndrome, highlighting important diagnostic and management approaches but reporting no new research results.

This article provides a critical overview of recent discoveries in the genetics and molecular processes involved in androgenetic alopecia, focusing on its polygenic basis and DHT dependency, but reports no new clinical results.

The document concludes that research on sulfatase inhibitors should continue due to their potential in treating various diseases, despite some clinical trial failures.

This review compiles current information about Eclipta prostrata, traditional uses, and its promising pharmacological properties, like hepatoprotective and anti-inflammatory effects, but emphasizes that more research is needed to fully understand its mechanisms and ensure safety for clinical application.

This review discusses the role of hormonal dysregulation and metabolic syndrome in hidradenitis suppurativa and reports no new clinical results.

This study suggests that daughters of women with PCOS may have altered androgen metabolism in early childhood, with increased 5α-reductase activity potentially contributing to PCOS development.

This study suggests that chronic stress can lead to decreased skin pigmentation in mice by disrupting the skin's HPA axis, potentially making stress a risk factor for depigmentation.

This article provides an overview of recent discoveries about steroidogenic enzymes involved in androgenetic alopecia but reports no new clinical results.

Hormonal treatments are effective as a second-line option for moderate-to-severe acne in females, but should be used with caution due to health risks.

This study found that biallelic LSS mutations lead to congenital hypotrichosis and cataracts, with each tissue-specific loss of function observed in mouse models.

This study found that millimolar concentrations of minoxidil in the skin induced VEGF production through HIF-1 stabilization by inhibiting PHD-2, implying a molecular mechanism for hair growth promotion.

This review discusses the role of steroid sulfatase in steroid hormone metabolism and highlights the need for more research on its expression and regulation, especially regarding hormone-dependent tumors.

Local skin glucocorticoid production is crucial for healthy skin, and its disruption can lead to skin diseases.

This study found that male and female chicken feather morphology and color patterns can be extrinsically modified through molting and resetting the stem cell niche during regeneration.

This study found that a blackcurrant extract with phytoestrogen activity increased hair number and stem cell marker expression in a menopausal rat model, suggesting a potential benefit for hair loss.

This review examines rodent models to explore how maternal conditions like undernutrition, obesity, hypoxia, and androgen exposure affect fetal programming and metabolic outcomes in offspring, but presents no new clinical findings.

This study suggests that porphyra-334 may have antiaging properties, promoting collagen synthesis, improving periorbital wrinkles, and supporting hair follicle growth through gene regulation.

This study identified distinct gene expression programs in keratinocytes responsible for forming hard scales and soft interscale epidermis in chickens, revealing conserved differentiation genes similar to those in human skin.

This study reported unexpected positive results in two males with androgenetic alopecia using a cyclodextrin-enabled, natural-based formula over 270 days, showing marked hair thickening and reduced scalp hair loss.

This review discusses biotin's role in nutrition and suggests no benefit to supplementing it for hair, nails, and skin in healthy individuals; it reports preliminary findings that high dosages may help some multiple sclerosis patients.

This source emphasizes that menopause affects the onset and course of certain skin conditions, urging dermatologists to consider menopausal status and hormone therapy when treating skin diseases, while also calling for more diverse, dermatology-focused research to improve personalized care.

This review concluded that for women, the benefits of testosterone implants are outweighed by risks, with possible higher rates of irreversible adverse effects than previously reported.