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A substance called 15-deoxy prostaglandin J2 can cause hair follicle cells to die, which might explain how prostaglandin D2 can lead to hair loss.

Higher levels of the DP2 receptor may lead to hair loss.

PGD2 stops hair growth and is higher in bald men with AGA.

Topical cetirizine improves hair density and thickness in androgenetic alopecia, but more research is needed.

Certain drugs are effective for skin conditions like psoriasis, vitiligo, and hair loss.

Targeting the PGD2-DP2 pathway may help treat hair loss.

PGD2 increases androgen receptor activity in hair cells, which could be targeted to treat hair loss.

Western diet may cause male pattern baldness; low glycemic diet with magnesium could help.

New treatments for hair loss should target eight main causes and use specific plant compounds and peptides for better results.

New nanocarriers improve skin drug delivery with low toxicity at certain concentrations.

Hair restoration surgery effectively treats hair loss with natural-looking results, using techniques like stem cells and platelet-rich plasma.

The review suggests that while many AKR1C3 inhibitors show promise for treating certain cancers, more research is needed to confirm their effectiveness in humans.

Different human hair follicle stem cells grow at different rates and respond differently to a baldness-related compound.

Prostaglandins and the enzyme AKR1C3 could play a role in skin cancer and hair loss, and further research is needed to understand these mechanisms.

A substance called prostaglandin D2 is found more in bald scalps and it stops hair from growing. Blocking its receptor could potentially treat hair loss.

Prostaglandin D2, found in higher levels in bald scalps, stops hair growth, suggesting that blocking its receptor could potentially treat hair loss.

Prostaglandin D2 increases testosterone production in skin cells through a process involving reactive oxygen species, and antioxidants may help treat hair loss.

CRTH2 antagonists might be useful for treating many conditions because they play a role in immune and inflammation responses.

Sebaceous glands play a key role in skin health, immunity, and various skin diseases.

Prostaglandin D2, found in higher levels in bald scalps, stops hair growth and could be a target for treating hair loss.

PPARγ is crucial for skin health but can have both beneficial and harmful effects.

Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

PPARγ is essential for maintaining healthy skin, controlling inflammation, and ensuring proper skin barrier function.

15-lipoxygenase helps keep skin healthy by reducing inflammation.

A substance called compound-1 could help increase hair growth by maintaining prostaglandin levels in hair follicles.

The inhibitor DPP can promote hair growth.

Low-dose acitretin helps nail psoriasis, stem cells may treat scarring alopecia, Chinese men have lower baldness rates, lateral foldplasty is good for ingrown toenails, hair diameter helps diagnose female baldness, childhood trauma linked to alopecia areata, certain hair-weaving leads to scalp conditions in African American women, and new methods for hair research and understanding hair and sweat gland development were introduced.