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Different skin cells process testosterone differently, and certain drugs can change this process, possibly helping treat acne and hair loss.

Normal-range ALT levels can indicate metabolic and hormonal imbalances in young women.

Trilostane effectively treated hair loss in Alaskan Malamutes with no adverse effects.

The document highlights various patents for new compounds with potential treatments for multiple diseases, including cancer, hormonal disorders, and diabetes.

Baicalin may help reduce excessive male hormone levels in PCOS.

Testosterone helps human pancreatic cells increase insulin release.

Selective non-steroidal inhibitors of 5α-reductase type 1 can help treat DHT-related disorders.

New compounds show promise for treating hair loss, enlarged prostate, and prostate cancer, with some being more effective and having different side effects than current treatments.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

Sulforaphane may help with hair growth by breaking down a hormone that causes hair loss.

Androgens play a complex role in skin conditions like acne and hair loss in women, and normal blood levels don't always show true androgen status.

PCOS has a strong genetic basis, but more research is needed to fully understand it.

The document suggests that Alopecia X in dogs is mainly a cosmetic issue and might be better left untreated.

DHT affects bone growth by altering gene activity in osteoblasts, potentially complicating steroid use.

Women with a certain type of tumor had higher levels of pregnancy hormone and male hormones, which decreased after treatment.

Men and women experience skin aging differently due to changes in sex hormone levels with age.

Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.

Inflammation may be linked to hair loss, and targeting specific enzymes could help treat it.

Vitamin E affects liver metabolism, enhancing stress resistance, reducing blood clotting, and altering hormone processing.

Men with early balding showed higher levels of certain genes linked to hair loss and possibly prostate cancer.

Acne can't be cured but can be managed with treatments like benzoyl peroxide and diet changes; it's costly and can lead to scarring and mental health issues.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

A brain-produced steroid causes increased scratching in mice with a skin condition similar to eczema.

PCOS is a complex condition that affects women's hormonal balance and metabolism, requiring lifestyle changes and medical management.

Hair loss in Androgenetic Alopecia is caused by genetics, aging, and lifestyle, leading to hair follicle shrinkage and related health risks.

5-alpha reductase inhibitors might worsen lung recovery in COVID-19 patients, suggesting a pause in their use.

Hormones, especially testosterone and DHT, are key for penis development and function, and testosterone therapy may help with erectile dysfunction in those with low levels.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

Certain steroids in the brain affect mood and symptoms of depression, and treatments targeting these steroids show promise for improving these symptoms.

5-alpha reductase deficiency leads to male sexual development issues and treatments like finasteride help with prostate enlargement and hair loss.