78 citations,
November 2005 in “Endocrinology” Hairless protein can block vitamin D activation in skin cells.
1308 citations,
March 1998 in “Journal of bone and mineral research” The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.
79 citations,
January 2017 in “Dermatology practical & conceptual” Correcting nutrient deficiencies may help with hair loss, but the benefits of supplements without a deficiency are uncertain and could be harmful.
51 citations,
January 2012 in “Annals of dermatology/Annals of Dermatology” A boy with alopecia regrew hair using a vitamin D cream after other treatments failed.
81 citations,
January 2006 in “Journal of cellular physiology” Mice without the vitamin D receptor gene lose hair due to disrupted hair follicle cycles.
1 citations,
January 2015 in “Journal of Pigmentary Disorders” Melasma is a skin condition linked to female hormones, genetics, UV exposure, and certain medications, but not to pituitary, adrenal, or thyroid diseases.
48 citations,
April 2013 in “Expert Opinion on Investigational Drugs” Possible new treatments for common hair loss include drugs, stem cells, and improved transplants.
86 citations,
October 2005 in “Experimental Dermatology” The Foxn1 gene mutation causes hairlessness and immune system issues, and understanding it could lead to hair growth disorder treatments.
42 citations,
March 2008 in “Molecular and Cellular Endocrinology” Hormones and neuroendocrine factors control hair growth and color, and more research could lead to new hair treatment options.
277 citations,
June 2003 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” Epithelial-mesenchymal interactions control hair growth cycles through specific molecular signals.
63 citations,
May 2017 in “American Journal of Clinical Dermatology” People with alopecia areata often have lower levels of vitamin D, zinc, and folate, but more research is needed to understand if supplements can help treat it.
14 citations,
April 2000 in “Animal Science/Animal science” Nutrients like vitamins, copper, zinc, and amino acids are crucial for healthy hair and wool growth.
9 citations,
November 2014 in “Journal of Cutaneous Medicine and Surgery” Many dermatologists in Saudi Arabia recommend vitamins and minerals for hair loss, often based on personal experience rather than strong evidence.
134 citations,
December 2018 in “Dermatology and Therapy” Some vitamins and minerals like vitamin D and iron can help with certain types of hair loss, but more research is needed for others.
Vitamin D is crucial for skin health and managing skin diseases.
180 citations,
January 2002 in “The journal of investigative dermatology/Journal of investigative dermatology” Vitamin D Receptor is crucial for normal skin and hair growth.
25 citations,
June 2017 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” VDR regulation varies by tissue and is crucial for its biological functions.
47 citations,
October 1989 in “European Journal of Pediatrics” Two siblings stayed rickets-free for 14 years after stopping treatment.
139 citations,
September 2001 in “The journal of investigative dermatology/Journal of investigative dermatology” Mutations in the Vitamin D receptor gene can cause hair loss similar to mutations in the Hairless gene.
76 citations,
January 2010 in “Journal of bone and mineral metabolism” 15 citations,
March 2000 in “The journal of investigative dermatology/Journal of investigative dermatology” As skin cells mature, vitamin D receptor levels decrease while retinoid X receptor α levels increase.
January 2021 in “Turkiye Klinikleri Journal of Dermatology” Many young men with hair loss have low levels of vitamin D and B12.
22 citations,
November 2016 in “International journal of molecular sciences” Vitamin D receptor is important for regulating hair growth and wound healing in mice.
123 citations,
December 1997 in “Calcified Tissue International” Higher androgen levels and site-specific AR expression cause sex-related skeletal differences, and certain steroids can boost AR expression and androgen effects in bone cells.
104 citations,
May 2003 in “Endocrinology” Lampreys have a functional vitamin D receptor that may help detoxify harmful substances.
September 2005 in “CRC Press eBooks” Vitamin D is important for skin cell growth and health, and its active form and receptor play key roles in skin and hair processes.
36 citations,
February 2007 in “Journal of biological chemistry/The Journal of biological chemistry” The vitamin D receptor can work without its usual activating molecule.
11 citations,
January 2017 in “Biochemical and biophysical research communications” 1α,25-dihydroxyvitamin D3 directly affects cartilage growth and development.
18 citations,
July 2010 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” The vitamin D receptor helps regulate skin and hair health independently of its usual vitamin D ligand.
11 citations,
June 1996 in “Nutrition” Vitamin D3 may prevent hair loss from chemotherapy, but side effects and cancer cell protection are concerns.