research Sebocytes Are the Key Regulators of Androgen Homeostasis in Human Skin
Sebocytes play a key role in controlling androgen levels in human skin.
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research Exploring the Potential Routine Use of Electronic Healthcare Record Data to Strengthen Early Signal Assessment in UK Medicines Regulation: Proof-of-Concept Study
Using electronic health records can help identify drug side effects but has some limitations.
research Hormonal, Medical, and Nonsurgical Aspects of Gender Affirmation
The document concludes that gender-affirming treatments are essential for transgender individuals and outlines safe hormone therapy practices.
research Characterization of X-Linked Hypohidrotic Ectodermal Dysplasia Hair and Sweat Gland Phenotypes Using Phototrichogram Analysis and Live Confocal Imaging
People with X-linked hypohidrotic ectodermal dysplasia have no sweat ducts and less, thinner hair.
research Immunohistochemical Evaluation of Androgen Receptor and Nerve Structure Density in Human Prepuce from Patients with Persistent Sexual Side Effects after Finasteride Use for Androgenetic Alopecia
Finasteride, a hair loss drug, may cause long-term sexual side effects due to changes in hormone receptor levels.
research Features
Pharmacists play a key role in helping patients use over-the-counter products correctly, including those for hair regrowth and smoking cessation.
research Hair Regrowth Treatment Efficacy and Resistance in Androgenetic Alopecia: A Systematic Review and Continuous Bayesian Network Meta-Analysis
ALRV5XR is the most effective hair regrowth treatment at 24 weeks.
research Use of Botulinum Toxin for Androgenic Alopecia: A Systematic Review
Botulinum toxin injections can help treat common hair loss in men, but more research is needed to confirm this and understand how it works.
research Accelerated Hair Growth by Combining Thread Monofilament and Minoxidil in Female Androgenetic Alopecia
Thread monofilament and minoxidil together increase hair growth in female androgenetic alopecia.
research Androgenic Alopecia: Cross-Talk Between Cell Signal Transduction Pathways
Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.
research A Study of the Androgen Receptor Gene Polymorphism and the Level of Expression of the Androgen Receptor in Androgenetic Alopecia Among Egyptians
The study suggests that a specific gene variation and higher gene activity are linked to increased baldness in Egyptian men.
research Evaluation of Hair Growth Promoting Activity of Musa Paradisiaca Unripe Fruit Extract
Unripe banana extract may promote hair growth similar to minoxidil.
research Two Different Trichoscopic Patterns of Mid-Frontal Scalp in Patients with Frontal Fibrosing Alopecia and Clinical Features of Androgenetic Alopecia
Two trichoscopic patterns found in hair loss: diffuse fibrotic and androgenetic alopecia, affecting treatment choice and regrowth chances.
research Polycystic Ovarian Syndrome: Comprehensive Diagnosis and Treatment Approaches
The document concludes that managing PCOS requires a comprehensive approach, including lifestyle changes and medication, to improve symptoms and reduce health risks.
research A Comparative Study of Different Treatment Modalities of Polycystic Ovarian Syndrome in Women of Reproductive Age Group at Tertiary Care Centre
Combining letrozole with metformin is the most effective treatment for inducing pregnancy in women with PCOS.
research Hair Disorders
Understanding normal hair growth and loss in children is key to diagnosing and treating hair disorders.
research The Biological Role of Platelet Derivatives in Regenerative Aesthetics
Platelet-derived products help regenerate tissue and are used in various skin and hair treatments.
research The Efficacy of Topical Minoxidil 2% Versus Topical Botanically Derived Inhibitors of 5 Alpha Reductase in Treatment of Female Pattern Hair Loss by Trichoscopy
Minoxidil 2% is more effective for female hair loss, but botanicals have fewer side effects.
research Androgenic Alopecia Is Associated With Higher Dietary Inflammatory Index And Lower Antioxidant Index Scores
Antioxidant-rich diets may reduce hair loss risk, while pro-inflammatory diets may increase it, especially in women.
research A Marine Protein-Based Dietary Supplement for Subclinical Hair Thinning/Loss: Results of a Multisite, Double-Blind, Placebo-Controlled Clinical Trial
The supplement helps improve hair growth and reduce hair shedding.
research A Comprehensive Review of Platelet-Rich Plasma for the Treatment of Dermatologic Disorders
Platelet-rich plasma can increase hair density and may help treat some skin conditions, but it's costly, not FDA-approved, and needs more research.
research Book Review: Pediatric Endocrinology: A Practical Clinical Guide
The book is a comprehensive and current guide on hair disorders, with minor flaws.
research Book Review: Disorders of Hair Growth: Diagnosis and Treatment, Second Edition
The book is a comprehensive resource on hair disorders, but lacks information on some conditions.
research The Risk of Psychiatric Disorders in Finasteride Users with Benign Prostatic Hyperplasia and Androgenetic Alopecia: A Population-Based Case-Control Study
Finasteride users have a very low risk of mental health issues, but those with hair loss may have slightly higher anxiety and depression.
research FC056 The Ideal Catagen of the Hair
Blocking IL-1 could help treat some hair loss conditions; alopecia affects liver detox systems; spironolactone is better than finasteride for female hair growth; focusing on the catagen hair phase could lead to new alopecia treatments.
research The Experts Meetings on Psoriasis: Recommendations for Daily Practice
Tofacitinib shows promise for treating severe alopecia areata with good safety and effectiveness.
research Geographical Differences in Demographics and Fertility Histories of Men Presenting for Infertility Evaluation Between the United States and Canada: Results from the Andrology Research Consortium
American men seeking infertility evaluation are generally older, more obese, have longer infertility duration, and different lifestyle habits compared to Canadian men.
research Follow-Up of 1 mg Finasteride Treatment of Male Pattern Baldness: Difference Between Clinical Trials and Private Office Follow-Up
Most men stopped using finasteride for baldness due to unsatisfactory results or were lost to follow-up, and those who continued saw minimal to moderate improvement.
research Follow-Up of 1 mg Finasteride Treatment of Male Pattern Baldness: Differences Between Clinical Trials and Private Office Follow-Up and Influences on Prescribing Habits Evaluated
Finasteride showed limited hair growth and low patient compliance in treating male pattern baldness.
research Non-Neoplastic Disorders of Hair
The document concludes that different types of hair loss have specific treatments, and early diagnosis is crucial for preventing permanent hair loss.