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Did you mean Lymphocytic Infiltrate?

GlossaryLymphocytic Infiltrate

accumulation of immune cells in tissue causing inflammation

Lymphocytic infiltrate refers to the accumulation of lymphocytes, a type of white blood cell, in a particular tissue. This often occurs as part of the body's immune response to infection, inflammation, or autoimmune conditions, where the immune system mistakenly attacks healthy cells. In the context of hair and alopecia, lymphocytic infiltrate can be seen in conditions like alopecia areata, where these immune cells target hair follicles, leading to hair loss.

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research Alopecia Areata with Lymphocytic Mural Folliculitis Affecting the Isthmus in a Thoroughbred Mare

14 citations, August 2004 in “Veterinary Dermatology”

The horse had a rare type of hair loss caused by immune cells attacking hair follicles.

research Letter in Reply: Alopecia Areata After SARS-CoV-2 Vaccination

3 citations, May 2022 in “JAAD case reports”

A woman developed alopecia after her second Pfizer vaccine but regrew her hair with treatment and had no issues after a booster shot.

research Frontal Fibrosing Alopecia in Postmenopausal Women

179 citations, December 2004 in “Journal of The American Academy of Dermatology”

Some postmenopausal women with frontal fibrosing alopecia stopped losing hair with finasteride treatment, hinting at a possible hormonal cause.

research Discoid Lupus Alopecia Complicated by Frontal Fibrosing Alopecia on a Background of Androgenetic Alopecia

25 citations, March 2013 in “British Journal of Dermatology”

Woman has discoid lupus, frontal fibrosing, and androgenetic alopecia.

research Frontal Fibrosing Alopecia Versus Lichen Planopilaris: A Clinicopathological Study

126 citations, April 2006 in “International Journal of Dermatology”

The conclusion is that FFA and LPP have similar scalp biopsy features, making them hard to distinguish histologically, and FFA may be a specific kind of scarring hair loss.

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community Diffuse hair loss and scalp biopsies

in Research 692 upvotes 4 months ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community The Worst Hair Loss Condition You (MAY) have: LPP

in Research/Science 43 upvotes 3 months ago

Lichen Planopilaris (LPP) is an autoimmune condition causing permanent hair loss and fibrosis, often misdiagnosed. Treatments include pioglitazone, topical corticosteroids, anti-inflammatory medication, and Jak inhibitors.

community Lost density 60% all over scalp in 120 days (4months)

in Update 10 upvotes 6 months ago

A user lost 60% hair density in 4 months, started finasteride and microneedling, and has greasy, flaky, yellowish scalp. They are awaiting biopsy results, and another user suggested trying ketoconazole shampoo.