Diffusion Properties of Model Compounds in Artificial Sebum

    Satyanarayana Valiveti, Guang Wei Lu
    Studysummary This study found that drug transport through artificial sebum varies depending on the compound, suggesting that sebum-targeted delivery can be optimized by selecting compounds based on their distinct transport profiles in sebum versus skin.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on sciencedirect.com →
    Discuss this study in the Community →

    Research cited in this study 7

    1. Investigation of Drug Partition Property in Artificial Sebum International Journal of Pharmaceutics · 2007
    2. Follicular Targeting: A Promising Tool in Selective Dermatotherapy ˜The œjournal of investigative dermatology. Symposium proceedings/˜The œJournal of investigative dermatology symposium proceedings · 2005
    3. Transfollicular Drug Delivery: Is It a Reality? International journal of pharmaceutics · 2005
    4. Penetration Profile of Microspheres in Follicular Targeting of Terminal Hair Follicles ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2004
    5. Penetration and Distribution of Three Lipophilic Probes in Human Skin Focusing on the Hair Follicle Journal of controlled release · 2002
    6. Evaluation of the Hairless Rat as a Model for In Vivo Percutaneous Absorption Journal of Pharmaceutical Sciences · 1997
    7. Role of Transepidermal and Transfollicular Routes in Percutaneous Absorption of Steroids: In Vitro Studies on Human Skin Skin Pharmacology and Physiology · 1994