The Biology And Genetics Of Curly Hair
March 2017
in “
Experimental Dermatology
”
Research cited in this study
40 / 40 resultsresearch Mutations in Three Genes Encoding Proteins Involved in Hair Shaft Formation Cause Uncombable Hair Syndrome
Mutations in three genes cause Uncombable Hair Syndrome, leading to frizzy hair that can't be combed flat.
research A Genome-Wide Association Scan in Admixed Latin Americans Identifies Loci Influencing Facial and Scalp Hair Features
research The Epidermal Growth Factor Receptor Decreases Stathmin 1 and Triggers Catagen Entry in the Mouse
EGFR helps mouse hair follicles stop growing by reducing certain growth regulators.
research Evaluation of the Predictive Capacity of DNA Variants Associated with Straight Hair in Europeans
Certain DNA variants can predict straight hair in Europeans but are not highly specific.
research Keratins: the hair shaft's backbone revealed
The document discussed the critical role of keratins in hair structure and disorders, highlighting their function in forming intermediate filaments essential for hair and skin integrity. It detailed how mutations in specific keratin genes, such as KRT81, KRT83, and KRT86, lead to hair disorders like monilethrix, characterized by fragile, beaded hair. The study by van Steensel et al. expanded the mutation spectrum of monilethrix by identifying additional cases linked to KRT83 mutations, reinforcing its role in the disorder. The variability in hair phenotype among monilethrix patients remained unexplained, suggesting further research into other hair cortex components could provide insights into hair strength and structure.
research The Dermal Papilla: An Instructive Niche for Epithelial Stem and Progenitor Cells in Development and Regeneration of the Hair Follicle
The dermal papilla is crucial for hair growth and health, and understanding it could lead to new hair loss treatments.
research Hair Curvature: A Natural Dialectic and Review
The document concludes that hair curvature can be explained by the growth patterns caused by the shape and separation of cells in the hair follicle and is affected by specific molecular pathways.
research Dermal Papilla Cell Number Specifies Hair Size, Shape, and Cycling, and Its Reduction Causes Follicular Decline
More dermal papilla cells in hair follicles lead to larger, healthier hair, while fewer cells cause hair thinning and loss.
research The Biology of Hair Diversity
Hair diversity is influenced by complex genetics and environmental factors, requiring more research for practical solutions.
research Diseases That Turn African Hair Silky
Certain diseases like AIDS and lupus can make African hair become silky.
research A Missense Mutation within the Helix Initiation Motif of the Keratin K71 Gene Underlies Autosomal Dominant Woolly Hair/Hypotrichosis
research Characterization of the Human Hair Keratin–Associated Protein 2 (KRTAP2) Gene Family
research Congenital Hair Loss Disorders: Rare, But Not Too Rare
Some hair loss disorders are caused by genetic mutations affecting hair growth.
research Autosomal-Dominant Woolly Hair Resulting from Disruption of Keratin 74 (KRT74), a Potential Determinant of Human Hair Texture
research Common Variants in the Trichohyalin Gene Are Associated with Straight Hair in Europeans
Common variants in the Trichohyalin gene are linked to straight hair in Europeans.
research Transglutaminase-3 Enzyme: A Putative Actor in Human Hair Shaft Scaffolding?
TGase 3 helps build hair structure by forming strong bonds between proteins.
research Molecular Elements of the Regulatory Control of Keratin Filament Modulator AHF/Trichohyalin in the Hair Follicle
The study concluded that a protein important for hair strength is regulated by certain molecular processes and is affected by growth phases.
research Enhanced Ectodysplasin-A Receptor Signaling Alters Multiple Fiber Characteristics to Produce the East Asian Hair Form
A genetic change in the EDAR gene causes the unique hair traits found in East Asians.
research Human Hair Keratin Network And Curvature
Curly hair shape is due to uneven growth patterns in the hair follicle.
research Worldwide Diversity of Hair Curliness: A New Method of Assessment
A new method accurately classifies hair types, showing global hair diversity.
research Shape Variability and Classification of Human Hair: A Worldwide Approach
Human hair can be classified into eight types based on physical features, not ethnicity.
research Involvement of the Edar Signaling in the Control of Hair Follicle Involution (Catagen)
Edar signaling is crucial for controlling hair growth and regression.
research Biology of the Wool Follicle: An Excursion into a Unique Tissue Interaction System Waiting to Be Rediscovered
The article concludes that the wool follicle is a valuable model for studying tissue interactions and has potential for genetic improvements in wool production.
research Peptidylarginine Deiminase Isoforms Are Differentially Expressed in the Anagen Hair Follicles and Other Human Skin Appendages
research Runx3 Is Involved in Hair Shape Determination
Runx3 helps determine hair shape.
research The Human Type I Keratin Gene Family: Characterization of New Hair Follicle Specific Members and Evaluation of the Chromosome 17q21.2 Gene Domain
The study identified and characterized new keratin genes linked to hair follicles and epithelial tissues.
research Comparative aspects of the inner root sheath in adult and developing hairs of mammals in relation to the evolution of hairs
research Fine Structure and Immunocytochemistry of Monotreme Hairs, with Emphasis on the Inner Root Sheath and Trichohyalin-Based Cornification During Hair Evolution
Monotreme hair structure and protein distribution are similar to other mammals, but their inner root sheath cornifies differently, suggesting a unique evolution from reptile skin.
research Trichohyalin Mechanically Strengthens the Hair Follicle
Trichohyalin makes hair follicles stronger.
research Hair Shape of Curly Hair
Curly hair shape is determined by the hair bulb.
research Hair Keratin Pattern in Human Hair Follicles Grown In Vitro
Human hair follicles grown in vitro maintain normal keratin patterns and structure.
research K6irs1, K6irs2, K6irs3, and K6irs4 Represent the Inner-Root-Sheath-Specific Type II Epithelial Keratins of the Human Hair Follicle1
research Straight Hair Associated with Interferon-Alpha Plus Ribavirin in Hepatitis C Infection
ALA-PDT is effective and safe for chronic X-ray dermatitis, providing complete or partial remission.
research A Novel Epithelial Keratin, hK6irs1, Is Expressed Differentially in All Layers of the Inner Root Sheath, Including Specialized Huxley Cells of the Human Hair Follicle
A new keratin, hK6irs1, is found in all layers of the hair follicle's inner root sheath.
research Differences in Hair Follicle Dermal Papilla Volume Are Due to Extracellular Matrix Volume and Cell Number: Implications for the Control of Hair Follicle Size and Androgen Responses
Hair follicle size is mainly influenced by the number of cells and extracellular matrix volume, with cell number having a larger impact.
research Trichohyalin: A Structural Protein of Hair, Tongue, Nail, and Epidermis
research The Secret Life of the Hair Follicle
Hair follicles create different cell layers and proteins, controlled by various molecules.
research An In Vitro Model for the Study of Human Hair Growth
Researchers created a lab model to study human hair growth, showing it can grow and self-regulate outside the body.
research The Origin of Citrulline-Containing Proteins in the Hair Follicle and the Chemical Nature of Trichohyalin, an Intracellular Precursor
research Neogenesis of Human Hair Follicles
Human hair follicles can grow back.
Related Research
9 / 9 resultsresearch The disruption of Sox21-mediated hair shaft cuticle differentiation causes cyclic alopecia in mice
research Characterization and expression analysis of the hair keratin associated protein KAP26.1
research Hair Follicle-Specific Keratins And Their Diseases
Only a few hair-specific keratins are linked to inherited hair disorders.
research Keratins of the Human Hair Follicle
research Hair follicle differentiation and regulation.
research Hair Keratin Pattern in Human Hair Follicles Grown In Vitro
Human hair follicles grown in vitro maintain normal keratin patterns and structure.
research Formation and Structure of Human Hair
research Effects of Epidermal Growth Factor on the Morphology and Patterns of DNA Synthesis in Isolated Human Hair Follicles
EGF makes hair follicles grow longer but stops hair production.