Serum Irisin And Insulin Resistance In Patients With Early-Onset Androgenetic Alopecia: A Case-Control Study

    September 2026 in “ Cutaneous and Ocular Toxicology ”
    Esra Ağaoğlu, Özben Özden Işıklar, Ilayda Kacer … Zeynep Nurhan Saraçoğlu
    Studysummary This study found no significant differences in serum irisin or insulin resistance between men with early-onset androgenetic alopecia and healthy controls, although AGA patients had higher BMI and waist circumference.
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    Research cited in this study 14

    1. Increased Prevalence of Insulin Resistance and Metabolic Syndrome in Men With Early-Onset Androgenetic Alopecia: A Case-Control Study Journal of Cosmetic Dermatology · 2025
    2. Factors Associated With Early-Onset Androgenetic Alopecia: A Scoping Review PLOS ONE · 2024
    3. Circulating and/or Cutaneous Irisin Resistance: A Novel Link Among Androgenetic Alopecia, Comorbid Metabolic Syndrome and Cardiovascular Risks Journal of Cosmetic Dermatology · 2023
    4. Association of Early-Onset Androgenetic Alopecia and Metabolic Syndrome JCPSP. Journal of the College of Physicians & Surgeons Pakistan · 2021
    5. Hyperuricemia Is Associated With Androgenetic Alopecia In Men: A Cross-Sectional Case-Control Study Journal of Cosmetic Dermatology · 2020
    6. The Association of Metabolic Syndrome and Insulin Resistance in Early-Onset Androgenetic Alopecia in Males: A Case-Control Study Indian Journal of Dermatology · 2019
    7. Serum Irisin: A Prognostic Marker for Severe Acne Vulgaris Journal of Cosmetic Dermatology · 2018
    8. Is Early Onset Androgenic Alopecia a Marker of Metabolic Syndrome and Carotid Artery Atherosclerosis in Young Indian Male Patients? International Journal of Trichology · 2015
    9. Androgenetic Alopecia, Metabolic Syndrome, and Insulin Resistance: Is There Any Association? A Case-Control Study Indian Dermatology Online Journal · 2014
    10. Association of Premature Androgenetic Alopecia and Metabolic Syndrome in a Young Indian Population International Journal of Trichology · 2014
    11. Higher Body Mass Index Is Associated With Greater Severity of Alopecia in Men With Male-Pattern Androgenetic Alopecia in Taiwan: A Cross-Sectional Study Journal of The American Academy of Dermatology · 2013
    12. The Investigation of Insulin Resistance and Metabolic Syndrome in Male Patients with Early-Onset Androgenetic Alopecia European Journal of Dermatology · 2011
    13. Androgenetic Alopecia and Cardiovascular Risk Factors in Men and Women: A Comparative Study Journal of The American Academy of Dermatology · 2010
    14. Obesity and Low-Grade Inflammation Among Young Finnish Men With Early-Onset Alopecia Dermatology · 2007