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    Improvement in Scalp Hair Appearance Following Treatment With a Non-Ablative Fractional Laser: A Retrospective Observational Study

    July 2025 in “ Lasers in Surgery and Medicine ”
    Marc R. Avram, Dawn Queen, Jerry Shapiro, Girish Gilly Munavalli
    Studysummary This study reported that a non-ablative fractional laser effectively improved visible hair growth and scalp appearance in both men and women with androgenetic alopecia, with a high success rate in identifying post-treatment improvements, and no adverse events were documented among the 132 patients evaluated.
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    Research cited in this study 26

    1. Progress of Clinical Research on Fractional Laser Treatment of Androgenetic Alopecia: A Review Article Journal of Cosmetic Dermatology · 2024
    2. Lasers in the Management of Alopecia: A Review of Established Therapies and Advances in Treatment Lasers in medical science · 2024
    3. Investigator-Blinded, Controlled, and Randomized Comparative Study on 1565 Nm Non-Ablative Fractional Laser Versus 5% Minoxidil for Treatment of Androgenetic Alopecia Journal of Cosmetic Dermatology · 2024
    4. Wound-Induced Hair Follicle Neogenesis as a Promising Approach for Hair Regeneration Molecules and Cells · 2023
    5. Androgenetic Alopecia: Therapy Update Drugs · 2023
    6. Treatment of Androgenetic Alopecia: Current Guidance and Unmet Needs Clinical, Cosmetic and Investigational Dermatology · 2023
    7. Efficacy and Safety of 1565-nm Non-Ablative Fractional Laser Versus Long-Pulsed 1064-nm Nd:YAG Laser in Treating Enlarged Facial Pores Lasers in medical science · 2022
    8. Treatment Options for Androgenetic Alopecia: Efficacy, Side Effects, Compliance, Financial Considerations, and Ethics Journal of Cosmetic Dermatology · 2021
    9. A Systematic Review and Meta-Analysis of Randomized Controlled Trials of United States Food and Drug Administration-Approved, Home-Use, Low-Level Light/Laser Therapy Devices for Pattern Hair Loss: Device Design and Technology PubMed · 2021
    10. Role of Low-Level Light Therapy in Androgenetic Alopecia Journal of Cutaneous and Aesthetic Surgery · 2021
    11. Low-Level Laser Therapy and Narrative Review of Other Treatment Modalities in Androgenetic Alopecia Lasers in Medical Science · 2020
    12. Laser-Assisted Hair Regrowth Plastic and reconstructive surgery. Global open · 2019
    13. Efficacy of 1,550-nm Erbium-Glass Fractional Laser Treatment and Its Effect on the Expression of Insulin-Like Growth Factor 1 and Wnt/β-Catenin in Androgenetic Alopecia Dermatologic Surgery · 2018
    14. Evidence-Based Guideline for the Treatment of Androgenetic Alopecia in Women and Men – Short Version Journal of The European Academy of Dermatology and Venereology · 2017
    15. Efficacy of Fractional Lasers in Treating Alopecia: A Literature Review Lasers in Medical Science · 2017
    16. Enhancing Hair Growth in Male Androgenetic Alopecia by a Combination of Fractional CO2 Laser Therapy and Hair Growth Factors Lasers in Medical Science · 2017
    17. Low-Level Light and Minoxidil 5% Combination Versus Either Modality Alone in Management of Female Patterned Hair Loss: A Randomized Controlled Study Lasers in Surgery and Medicine · 2017
    18. Adverse Effects and Safety of 5-Alpha Reductase Inhibitors (Finasteride, Dutasteride): A Systematic Review PubMed · 2016
    19. Drug Discovery for Alopecia: Gone Today, Hair Tomorrow Expert Opinion on Drug Discovery · 2015
    20. An Overview of Alopecias Cold Spring Harbor Perspectives in Medicine · 2014
    21. Efficacy and Safety of a Low-Level Laser Device in the Treatment of Male and Female Pattern Hair Loss: A Multicenter, Randomized, Sham Device-Controlled, Double-Blind Study American Journal of Clinical Dermatology · 2014
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    23. Low-Level Light Therapy for Androgenetic Alopecia: A 24-Week, Randomized, Double-Blind, Sham Device-Controlled Multicenter Trial Dermatologic Surgery · 2013
    24. The Effect of a 1550 Nm Fractional Erbium-Glass Laser in Female Pattern Hair Loss Journal of The European Academy of Dermatology and Venereology · 2011
    25. Fractional Photothermolysis Laser Treatment of Male Pattern Hair Loss Dermatologic Surgery · 2010
    26. HairMax LaserComb Laser Phototherapy Device in the Treatment of Male Androgenetic Alopecia Clinical Drug Investigation · 2009

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    1. Clinical Effects of Non-Ablative and Ablative Fractional Lasers on Various Hair Disorders: A Case Series of 17 Patients Journal of Cosmetic and Laser Therapy · 2013