Efficacy and Safety of Autologous Cell-Based Therapies for Atrophic Acne Scar Treatment: An Updated Systematic Review and Meta-Analysis with In-Depth Methodological and Clinical Insights

This study found that grafting an autologous cultured epithelial sheet improved both scarring and skin texture in four patients with acne-associated scar contracture three months post-treatment, suggesting the technique might effectively treat difficult acne scars by metabolizing excess collagen.

This review summarizes the use of autologous platelet concentrates in aesthetic medicine, finding promising results for facial treatments, but highlights the need for more rigorous research due to current study limitations.

This systematic review examined 64 randomized controlled clinical trials on regenerative medicine for specific dermatologic disorders, reporting up to 68.4% improvement in androgenetic alopecia and up to 71% improvement in vitiligo among 2888 patients.

This meta-analysis found that autologous epidermal cell suspensions reduce healing time, donor site size, operation time, pain scores, and complications in skin lesions. However, their impact on treatment area size, repigmentation, scar scale scores, and patient satisfaction was minimal.

This study reviews the use of nanofat in facial rejuvenation and cosmetic surgery, highlighting its potential for improving skin appearance and treating conditions like wrinkles and acne scars, yet emphasizes the need for further research into its long-term efficacy and safety.

This study found no evidence of increased keratinocyte proliferation in acne vulgaris, suggesting that other mechanisms may be responsible for hyperkeratinization in acne pathogenesis.

This review discusses wound healing options after skin excision and laser treatments for hidradenitis suppurativa and reports no new clinical results.

This review discusses the cosmetic applications of platelet-rich plasma in dermatology, highlighting its potential benefits and the need for more controlled studies.