Platelet‐rich plasma with low dose oral minoxidil (1.25mg versus 2.5mg) along with trichoscopic pre‐ and post‐treatment evaluation

    March 2021 in “Journal of Cosmetic Dermatology
    Abhijeet Kumar Jha, Zeeshan, Anupama Singh, Prasoon Kumar Roy
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    TLDR Combining platelet-rich plasma therapy with low dose oral minoxidil improved hair growth in men with hair loss, with slightly higher satisfaction at the higher minoxidil dose.
    This study assessed the effectiveness of combining platelet-rich plasma (PRP) therapy with two low doses of oral minoxidil (OM), 1.25 mg and 2.5 mg, in treating male androgenetic alopecia (MAGA). It involved 95 men aged 18-45 years, divided into two groups, with one group receiving 1.25 mg OM and the other 2.5 mg OM daily, both alongside PRP therapy, over a 6-month period. The results showed no statistically significant difference in hair count increase between the two groups, with Group A (1.25 mg OM) showing a 15.41% increase and Group B (2.5 mg OM) a 22.15% increase. However, patient satisfaction was significantly higher in Group B. The study suggests that the combination of low dose OM with PRP could be an alternative to finasteride or dutasteride for patients with MAGA, with a trend towards better satisfaction at the higher OM dose. The study calls for larger, long-term studies to confirm these findings.
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