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    Partial Alopecia Area Retains Bulge Hair Follicle Progenitor Cells in Indian Androgenetic Alopecia Patients

    September 2023 in “ bioRxiv (Cold Spring Harbor Laboratory) ”
    Akshay Hegde, Dyuti Saha, Savitha Somaiah, Colin Jamora

    Preprint — not peer reviewed. This was posted to a preprint server or data repository. It has not been through a journal's review process, and its findings may change or not hold up.

    Studysummary This study observed that while some progenitor cells were present in the partially bald areas of androgenic alopecia in Indian men, the completely bald areas lacked these cells, suggesting potential timing for therapeutic intervention targeting hair follicle stem cell activity.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 19

    1. Stem Cell Applications in Human Hair Growth: A Literature Review Cureus · 2023
    2. Treatment Options for Androgenetic Alopecia: Efficacy, Side Effects, Compliance, Financial Considerations, and Ethics Journal of Cosmetic Dermatology · 2021
    3. Progenitor-Cell-Enriched Micrografts as a Novel Option for the Management of Androgenetic Alopecia Journal of Cellular Physiology · 2019
    4. Expert Consensus on the Management of Androgenetic Alopecia in India International Journal of Trichology · 2019
    5. Androgens Modify Wnt Agonists/Antagonists Expression Balance in Dermal Papilla Cells Preventing Hair Follicle Stem Cell Differentiation in Androgenetic Alopecia Molecular and Cellular Endocrinology · 2016
    6. Impact of Androgenic Alopecia on the Quality of Life in Male Subjects: Results of an Observational Study from a Tertiary Care Hospital Journal of medical science and clinical research · 2016
    7. Stem Cell Therapy as a Novel Therapeutic Intervention for Resistant Cases of Alopecia Areata and Androgenetic Alopecia Journal of Dermatological Treatment · 2016
    8. Mapping the Expression of Epithelial Hair Follicle Stem Cell-Related Transcription Factors LHX2 and SOX9 in the Human Hair Follicle Experimental Dermatology · 2015
    9. Follicular Stem Cells in Androgenetic Alopecia Journal of Cytology and Histology · 2015
    10. Human Epithelial Hair Follicle Stem Cells and Their Progeny: Current State of Knowledge, the Widening Gap in Translational Research and Future Challenges BioEssays · 2014
    11. Androgenetic Alopecia: An Update Indian Journal of Dermatology, Venereology and Leprology · 2013
    12. Male Androgenetic Alopecia Is Due to Hair Follicle Stem Cell Inactivation Expert Review of Dermatology · 2011
    13. Bald Scalp in Men with Androgenetic Alopecia Retains Hair Follicle Stem Cells but Lacks CD200-Rich and CD34-Positive Hair Follicle Progenitor Cells Journal of Clinical Investigation · 2011
    14. Prevalence of Androgenetic Alopecia in China: A Community-Based Study in Six Cities British Journal of Dermatology · 2010
    15. Male Androgenetic Alopecia: Population-Based Study in 1,005 Subjects International Journal of Trichology · 2009
    16. Minoxidil: Mechanisms of Action on Hair Growth British Journal of Dermatology · 2004
    17. Androgenetic Alopecia: Pathogenesis and Potential for Therapy Expert Reviews in Molecular Medicine · 2002
    18. Androgenetic Alopecia in Men and Women Clinics in Dermatology · 2001
    19. The Transverse Anatomy of Androgenic Alopecia The Journal of Dermatologic Surgery and Oncology · 1990

    Related research 5

    1. Partial Alopecia Area Retains Bulge Hair Follicle Progenitor Cells in Indian Androgenetic Alopecia Patients bioRxiv (Cold Spring Harbor Laboratory) · 2023
    2. Stem Cell Applications in Human Hair Growth: A Literature Review Cureus · 2023
    3. The Mesenchymal Niche of the Hair Follicle Induces Regeneration by Releasing Primed Progenitors from Inhibitory Effects of Quiescent Stem Cells Cell Reports · 2018
    4. Bald Scalp in Men with Androgenetic Alopecia Retains Hair Follicle Stem Cells but Lacks CD200-Rich and CD34-Positive Hair Follicle Progenitor Cells Journal of Clinical Investigation · 2011
    5. From Surgery to Pharmacology to Gene Therapy: The Evolution of Hair Restoration Techniques Annals of Plastic Surgery · 2010