Parental Uveitis Causes Elevated Hair Loss in Offspring of C57BL/6J Mice

    March 2022 in “ Experimental Eye Research ”
    Jianping Liu, Guangnian Yin, Kaijiao Hu … Feilan Chen
    Studysummary This study suggests that in a moderately susceptible mouse population, parental uveitis affects the skin development and alters gene expression profiles related to various pathways in offspring without increasing susceptibility to autoimmune uveitis.
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    Research cited in this study 14

    1. Beware of the Impostors: Scalp Pathology Primer for the Hair Transplant Surgeon Indian Journal of Plastic Surgery · 2021
    2. Case Series: Gene Expression Analysis in Canine Vogt-Koyanagi-Harada/Uveodermatologic Syndrome and Vitiligo Reveals Conserved Immunopathogenesis Pathways Between Dog and Human Autoimmune Pigmentary Disorders Frontiers in Immunology · 2020
    3. Parental Uveitis Influences Offspring With an Increased Susceptibility to Experimental Autoimmune Uveitis Frontiers in Immunology · 2020
    4. LncRNA-PCAT1 Maintains Characteristics of Dermal Papilla Cells and Promotes Hair Follicle Regeneration by Regulating miR-329/Wnt10b Axis Experimental Cell Research · 2020
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    6. Msx2 Supports Epidermal Competency During Wound-Induced Hair Follicle Neogenesis Journal of Investigative Dermatology · 2018
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    8. Systemic Causes of Hair Loss Annals of Medicine · 2016
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    12. A Novel Point Mutation of Keratin 17 (KRT17) in a Japanese Family with Pachyonychia Congenita Type 2: An RNA-Based Genetic Analysis Using a Single Hair Bulb British Journal of Dermatology · 2008
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    14. Optimal Management of Hair Loss (Alopecia) in Children American Journal of Clinical Dermatology · 2003