Variation in Ovine KRTAP13-3 and Its Association with Wool Characteristics in Chinese Tan Sheep

April 2025 in “ Animals ”

Lingrong Bai, Huitong Zhou, Jinzhong Tao, Jon G. H. Hickford

Studysummary In this study, nucleotide sequence variation in the <i>KRTAP13-3</i> gene was associated with changes in heterotypic hair fibre diameter variation in Chinese Tan sheep.

Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer

View this study on mdpi.com →

Discuss this study in the Community →

Research cited in this study

10 / 10 results

research Characterization of Three Ovine KRTAP13 Family Genes and Their Association with Wool Traits in Chinese Tan Sheep

3 citations , October 2024 in “Animals”

This study identified three genes in the ovine KAP13 family on chromosome 1 and found that a specific allele of KRTAP13-2 is associated with improved wool fibre diameter uniformity in Chinese Tan sheep, suggesting its potential use as a marker for enhancing wool traits.

research The Complexity of the Ovine and Caprine Keratin-Associated Protein Genes

10 citations , November 2021 in “International journal of molecular sciences”

This review discusses the role of keratin-associated proteins in the growth and characteristics of wool and hair fibres from sheep and goats, and highlights areas for future research, but it presents no new findings.

research Variation In The Ovine Keratin-Associated Protein 15-1 Gene Affects Wool Yield

18 citations , September 2018 in “The Journal of Agricultural Science”

In this study, the presence of certain KAP15-1 gene variants in sheep was associated with differences in wool yield and fiber characteristics.

research Wool Keratin-Associated Protein Genes in Sheep: A Review

98 citations , May 2016 in “Genes”

This review explains the genetic diversity of sheep wool keratin-associated protein genes and explores how this variation might be leveraged for selective breeding to enhance wool fiber traits.

research Identification of the Keratin-Associated Protein 13-3 (KAP13-3) Gene in Sheep

26 citations , January 2011 in “Open Journal of Genetics”

In this study, researchers identified five unique sequences of the ovine KAP13-3 gene, with potential implications for wool traits due to observed amino acid changes.

research Characterization and Expression Analysis of the Hair Keratin Associated Protein KAP26.1

50 citations , July 2008 in “British Journal of Dermatology”

research Characterization of Human KAP24.1, A Cuticular Hair Keratin-Associated Protein with Unusual Amino Acid Composition and Repeat Structure

51 citations , January 2007 in “The journal of investigative dermatology/Journal of investigative dermatology”

This study identified a novel keratin-associated protein, KAP24.1, which is specifically expressed in the human scalp and located in the hair cuticle.

research Human KAP Genes: Only Half of It? Extensive Size Polymorphisms in Hair Keratin-Associated Protein Genes

53 citations , June 2005 in “The journal of investigative dermatology/Journal of investigative dermatology”

This article reviews extensive genetic polymorphisms in the keratin-associated proteins of human hair, indicating complexity but reporting no new clinical results and calls for further research on their potential impact on hair structure.

research Characterization of a First Domain of Human High Glycine-Tyrosine and High Sulfur Keratin-Associated Protein Genes on Chromosome 21q22.1

100 citations , December 2002 in “Journal of biological chemistry/The Journal of biological chemistry”

This study identified a domain on human chromosome 21q22.1 containing various high glycine-tyrosine and high sulfur keratin-associated protein genes, revealing their diverse expression in hair-forming cells.

Characterization of a Cluster of Human High/Ultrahigh Sulfur Keratin-Associated Protein Genes Embedded in the Type I Keratin Gene Domain on Chromosome 17q12-21

research Characterization of a Cluster of Human High/Ultrahigh Sulfur Keratin-Associated Protein Genes Embedded in the Type I Keratin Gene Domain on Chromosome 17q12-21

98 citations , June 2001 in “Journal of biological chemistry/The Journal of biological chemistry”

This study identified a cluster of genes on chromosome 17 related to hair keratin-associated proteins, including 37 genes forming seven multigene families, localized in the hair shaft's upper cortex.