Imprinted Dlk1-Gtl2 Cluster miRNAs Are Potential Epigenetic Regulators of Lamb Fur Quality

    October 2023 in “ BMC Genomics ”
    Letian Zhang, Jiankui Wang, Ganxian Cai … Xuemei Deng
    Studysummary This study identified miRNAs within the Dlk1-Gtl2 region on chromosome 18 as potential epigenetic regulators of lamb fur traits, with possible implications for the PI3K-AKT signaling pathway.
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    Research cited in this study 11

    1. Effects of the PI3K/Akt Signaling Pathway on the Hair Inductivity of Human Dermal Papilla Cells in Hair Beads Journal of Bioscience and Bioengineering · 2022
    2. Skin Transcriptome Analysis Identifies Key Genes Underlying Fur Development in Chinese Tan Sheep During Birth and Er-Mao Periods Gene · 2022
    3. Dynamic Changes of Genomic Methylation Profiles at Different Growth Stages in Chinese Tan Sheep Journal of Animal Science and Biotechnology/Journal of animal science and biotechnology · 2021
    4. PI3K/Akt Signaling Pathway Is Essential for De Novo Hair Follicle Regeneration Stem Cell Research & Therapy · 2020
    5. Integrated miRNA-mRNA Analysis Reveals Regulatory Pathways Underlying the Curly Fleece Trait in Chinese Tan Sheep BMC genomics · 2018
    6. Transcriptome Profile at Different Physiological Stages Reveals Potential Mechanism for Curly Fleece in Chinese Tan Sheep PloS one · 2013
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    10. Hepatocyte Growth Factor Activator Expressed in Hair Follicles Is Involved in In Vitro HGF-Dependent Hair Follicle Elongation Journal of Dermatological Science · 2001
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