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    Glossary Epigenetic Regulation

    chemical modifications that turn genes on or off

    Epigenetic Regulation refers to the process by which genes are turned on or off without changing the underlying DNA sequence. This is achieved through chemical modifications, such as DNA methylation and histone modification, which can influence gene expression and, consequently, cellular function. These changes can be influenced by environmental factors and can be heritable, playing a crucial role in development, disease, and adaptation.

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    1. Imprinted Dlk1-Gtl2 cluster miRNAs are potential epigenetic regulators of lamb fur quality BMC Genomics · 2023 · 1 citations
    2. Epigenetic regulations on skin wound healing: implications from current researches. PubMed · 2015 · 5 citations
    3. Identification of Epigenetic Regulator‐Associated Genes in Keloid Disease Through Integrated Bulk and Single‐Cell Transcriptomics With RT ‐ qPCR Validation The FASEB Journal · 2026
    4. Knockout of the ING5 epigenetic regulator confirms roles in stem cell maintenance and tumor suppression in vivo PLoS ONE · 2025
    5. INVESTIGATIONS INTO THE ROLE OF THE X-LINKED EPIGENETIC REGULATOR UTX (KDM6A) IN SELF-RENEWING STRATIFYING EPITHELIA Scholarly Commons (University of Pennsylvania) · 2025
    6. All Roads Go to the Nucleus: Integration of Signaling/Transcription Factor-Mediated and Epigenetic Regulatory Mechanisms in the Control of Skin Development and Regeneration Stem cell biology and regenerative medicine · 2018
    7. Hypoxia in Cell Reprogramming and the Epigenetic Regulations Frontiers in Cell and Developmental Biology · 2021 · 36 citations
    8. PROTACs in cancer therapy: targeted degradation of GPX4, PARP and epigenetic regulators Journal of Enzyme Inhibition and Medicinal Chemistry · 2026
    9. 0871 Skin longevity breakthroughs and targets for cellular age reversal: Sirtuins, key epigenetics regulators Journal of Investigative Dermatology · 2025
    10. Transcriptional and epigenetic mechanisms governing epidermal stem cell regulation Frontiers in Cell and Developmental Biology · 2026
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