Machine Learning Predicts Scarring Progression in Lichen Planopilaris: A Multidimensional Model Integrating Trichoscopy, Vitamin D, and Diagnostic Timelines

    September 2025 in “ International Journal of Medical Informatics ”
    Khaled Seetan, Almu’atasim Khamees, Raghad Yousef Yassin … Amir Majdi Moh’d
    Studysummary A machine learning model can predict scarring in lichen planopilaris using factors like vitamin D levels and diagnostic delay.
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    Research cited in this study 13

    1. Off-Label Use of Biologics and Janus Kinase Inhibitors for Scarring Alopecias: A Narrative Review Archives of Dermatological Research · 2025
    2. A Three-Step Diagnostic Algorithm for Alopecia: Pattern Analysis in Trichoscopy Journal of Clinical Medicine · 2025
    3. JAK Inhibitors in the Treatment of Lichen Planopilaris Skin Appendage Disorders · 2023
    4. Lichen Planopilaris and Frontal Fibrosing Alopecia: Review and Update of Diagnostic and Therapeutic Features Anais brasileiros de dermatologia/Anais Brasileiros de Dermatologia · 2022
    5. Frontal Fibrosing Alopecia Shows Robust T Helper 1 and Janus Kinase 3 Skewing British journal of dermatology/British journal of dermatology, Supplement · 2020
    6. Diffuse Variants of Scalp Lichen Planopilaris: Clinical, Trichoscopic, and Histopathologic Features of 40 Patients Journal of the American Academy of Dermatology · 2019
    7. Lichen Planopilaris: Retrospective Study on the Characteristics and Treatment of 291 Patients Journal of dermatological treatment · 2018
    8. Tofacitinib for the Treatment of Lichen Planopilaris: A Case Series Dermatologic therapy · 2018
    9. Pharmacologic Inhibition of JAK-STAT Signaling Promotes Hair Growth Science Advances · 2015
    10. A Case Series of 46 Patients With Lichen Planopilaris: Demographics, Clinical Evaluation, and Treatment Experience Journal of Dermatological Treatment · 2014
    11. Frontal Fibrosing Alopecia: A Multicenter Review of 355 Patients Journal of The American Academy of Dermatology · 2014
    12. Lichen Planopilaris Is Characterized By Immune Privilege Collapse Of The Hair Follicle's Epithelial Stem Cell Niche The Journal of Pathology · 2013
    13. Primary Cicatricial Alopecias: Clinicopathology of 112 Cases Journal of the American Academy of Dermatology · 2003