Evaluation of the Safety and Effectiveness of Intradermal Administration of QR678 Neo Hair Growth Factor Formulation: A Phase-IV, Open-Label, Single-Arm Multi-Ethnicity Clinical Trial

    January 2022 in “ Journal of Cosmetic Dermatology ”
    Aayna Clinic, Annette Asper, Apoorva Mittal … Vivek Singhal
    Studysummary This study found that intradermal administration of QR678 Neo® significantly reduced hair fall and improved hair growth in patients with androgenetic alopecia and female pattern hair loss, with no side effects reported during long-term follow-up.
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    Research cited in this study 24

    1. Effectiveness of QR678 and QR678 Neo with Intralesional Corticosteroid vs. Intralesional Corticosteroid Alone in the Treatment of Alopecia Areata – A Randomized, Comparative, Prospective Study Journal of Cosmetic Dermatology · 2021
    2. Evaluation of Efficacy of Intradermal Injection Therapy vs Derma Roller Application for Administration of QR678 Neo Hair Regrowth Formulation for the Treatment of Androgenetic Alopecia—A Prospective Study Journal of Cosmetic Dermatology · 2021
    3. QR 678 and QR678 Neo vs PRP—A Randomized, Comparative, Prospective Study Journal of Cosmetic Dermatology · 2020
    4. Female Pattern Hair Loss and Androgen Excess: A Report From the Multidisciplinary Androgen Excess and PCOS Committee The Journal of Clinical Endocrinology and Metabolism · 2019
    5. Intradermal Injections of a Hair Growth Factor Formulation for Enhancement of Human Hair Regrowth: Safety and Efficacy Evaluation in a First-in-Man Pilot Clinical Study Journal of Cosmetic and Laser Therapy · 2018
    6. The Effect of Autologous Activated Platelet-Rich Plasma Injection on Female Pattern Hair Loss: A Randomized Placebo-Controlled Study Journal of Cosmetic Dermatology · 2017
    7. Diet and Hair Loss: Effects of Nutrient Deficiency and Supplement Use Dermatology practical & conceptual · 2017
    8. Human Hair and the Impact of Cosmetic Procedures: A Review on Cleansing and Shape-Modulating Cosmetics Cosmetics · 2016
    9. Efficacy of Platelet-Rich Plasma in Treatment of Androgenic Alopecia Asian Journal of Transfusion Science · 2015
    10. Study of Platelet-Rich Plasma Injections in the Treatment of Androgenetic Alopecia Through a One-Year Period Journal of Cutaneous and Aesthetic Surgery · 2014
    11. Nutrition and Hair: The Role of Nutrients in Hair Health Dermatologic Clinics · 2012
    12. Nutrition and Hair Health: The Impact of Nutritional Deficiencies Clinics in Dermatology · 2010
    13. Autologous Platelet Rich Plasma (PRP): What Do We Know? Important Concepts Relevant to Hair Restoration Surgery Hair transplant forum international · 2010
    14. Gene-Wide Association Study Between the Aromatase Gene (CYP19A1) and Female Pattern Hair Loss British Journal of Dermatology · 2009
    15. Medical Treatments for Male and Female Pattern Hair Loss Journal of The American Academy of Dermatology · 2008
    16. Thymosin Beta 4 Induces Hair Growth Via Stem Cell Migration And Differentiation Annals of the New York Academy of Sciences · 2007
    17. The Effect of Tripeptide-Copper Complex on Human Hair Growth In Vitro Archives of Pharmacal Research · 2007
    18. Androgenetic Alopecia: Pathogenesis and Potential for Therapy Expert Reviews in Molecular Medicine · 2002
    19. Control of Hair Growth and Follicle Size by VEGF-Mediated Angiogenesis Journal of Clinical Investigation · 2001
    20. Incidence of Female Androgenetic Alopecia (Female Pattern Alopecia) Dermatologic Surgery · 2001
    21. Treatment of Hair Loss The New England Journal of Medicine · 1999
    22. Diffuse Female Hair Loss: Are Androgens Necessary? British Journal of Dermatology · 1999
    23. Finasteride in the Treatment of Men with Androgenetic Alopecia Journal of The American Academy of Dermatology · 1998
    24. Topical Minoxidil in Early Male Pattern Baldness Journal of The American Academy of Dermatology · 1985

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    5. Characteristic Features of Japanese Women's Hair With Aging and Hair Loss Journal of Dermatological Science · 2006
    6. Female-Patterned Alopecia in Teenage Brothers with Unusual Histologic Features Journal of Cutaneous Pathology · 2006
    7. Treatment of Hair Loss The New England Journal of Medicine · 1999
    8. Evaluation of Hair Loss Current problems in dermatology · 1996
    9. Disorders of Hair Growth: Diagnosis and Treatment McGraw-Hill eBooks · 1994