Global Burden of Alopecia Areata from 1990 to 2019 and Emerging Treatment Trends Analyzed Through GBD 2019 and Bibliometric Data

    July 2025 in “ Scientific Reports ”
    Hongfan Ding, Zhenghao Yu, Hongwu Yao, Xiao Xu, Yunxi Liu, Minliang Chen
    TLDR Alopecia areata affects women and young adults most, with low SDI regions seeing the highest increase, and new treatments like JAK inhibitors are being explored.
    The study analyzes the global burden of alopecia areata (AA) from 1990 to 2019, revealing that regions with low socio-demographic index (SDI) experienced the highest increase in disease burden, while high SDI regions saw a decrease but still bear the highest burden. Women and young adults (25-39 years) are more affected. Recent research focuses on clinical trials for treatments like JAK inhibitors and platelet rich plasma. The study highlights the need for further high-quality research to evaluate these treatments' long-term efficacy and safety, and provides insights for targeted prevention strategies and resource allocation.
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