Global Burden of Alopecia Areata from 1990 to 2019 and Emerging Treatment Trends Analyzed Through GBD 2019 and Bibliometric Data

    July 2025 in “ Scientific Reports ”
    Hongfan Ding, Zhenghao Yu, Hongwu Yao … Minliang Chen
    Studysummary This study observed that areas with low socio-demographic index showed the greatest rise in the disease burden of alopecia areata from 1990 to 2019, while high SDI areas still carried the highest burden overall.
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    Research cited in this study 27

    1. Alopecia Areata Treatment Patterns and Satisfaction: Results of a Real-World Cross-Sectional Survey in Europe Dermatology and Therapy · 2024
    2. Psychosocial Impact of Alopecia Areata in Pediatric and Adolescent Populations: A Systematic Review Journal of Paediatrics and Child Health · 2024
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    4. Janus Kinase Inhibitors for Alopecia Areata Journal of the American Academy of Dermatology · 2023
    5. Trichoscopy Patterns in Alopecia Areata: A Systematic Review and Meta-Analysis Skin Research and Technology · 2023
    6. Baricitinib for the Treatment of Alopecia Areata Drugs · 2023
    7. Efficacy and Safety of Ritlecitinib in Adults and Adolescents With Alopecia Areata: A Randomised, Double-Blind, Multicentre, Phase 2b–3 Trial The Lancet · 2023
    8. Efficacy and Safety of Baricitinib in Patients with Severe Alopecia Areata Over 52 Weeks in Phase III Trials American Journal of Clinical Dermatology · 2023
    9. Autologous Platelet-Rich Plasma Treatment for Androgenic Alopecia: A Systematic Review and Meta-Analysis of Clinical Trials on Patient Safety, Efficacy and Outcomes Plastic and Reconstructive Surgery · 2022
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    17. Ritlecitinib And Brepocitinib Demonstrate Significant Improvement In Scalp Alopecia Areata Biomarkers ˆThe ‰journal of allergy and clinical immunology/Journal of allergy and clinical immunology/˜The œjournal of allergy and clinical immunology · 2021
    18. Alopecia Areata: An Update on Etiopathogenesis, Diagnosis, and Management Clinical Reviews in Allergy & Immunology · 2021
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    20. The Psychosocial Burden of Alopecia Areata and Androgenetic Alopecia: A Cross-Sectional Multicentre Study Among Dermatological Outpatients in 13 European Countries Journal of the European Academy of Dermatology and Venereology · 2019
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    22. Human Scalp Hair: Modulation by Various Factors and Hormones - Do Estrogens Inhibit or Stimulate? A Perplexing Perspective Journal of Cosmetic Dermatology · 2019
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    24. Alopecia Areata and Health-Related Quality of Life: A Systematic Review and Meta-Analysis British Journal of Dermatology · 2016
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    26. Autologous Platelet-Rich Plasma: A Potential Therapeutic Tool for Promoting Hair Growth Dermatologic Surgery · 2012
    27. An Estrogen Receptor Pathway Regulates the Telogen-Anagen Hair Follicle Transition and Influences Epidermal Cell Proliferation Proceedings of the National Academy of Sciences of the United States of America · 1996

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