Consensus Document on the Clinical Management of Frontal Fibrosing Alopecia: Recommendations From Spanish Working Group on Trichology and Onychology of the AEDV

    December 2025 in “ Actas Dermo-Sifiliográficas ”
    David Saceda, A. Combalía, P. Fernandez-Crehuet … Sergio Vañó‐Galván
    Studysummary This consensus from 22 Spanish dermatologists recommends using a multimodal therapy starting with oral dutasteride, combined with topical and/or intralesional agents, and adding hydroxychloroquine if inflammation persists, to manage frontal fibrosing alopecia due to its irreversible hair loss and lack of specific approved treatments.
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    Research cited in this study 15

    1. A Review of Janus Kinase Inhibitor Use in Scarring Alopecia JAAD reviews. · 2025
    2. Gene-Environment Interaction Between CYP1B1 and Oral Contraception on Frontal Fibrosing Alopecia JAMA Dermatology · 2024
    3. Clinical Effectiveness of Finasteride Versus Hydroxychloroquine in the Treatment of Frontal Fibrosing Alopecia: A Randomized Controlled Trial Journal of Cosmetic Dermatology · 2023
    4. Janus Kinase Inhibition for the Treatment of Refractory Frontal Fibrosing Alopecia: A Case Series and Review of the Literature JAAD Case Reports · 2023
    5. Plasma Rich in Growth Factors as an Adjuvant Treatment for the Management of Frontal Fibrosing Alopecia: A Retrospective Observational Clinical Study Journal of Cutaneous Medicine and Surgery · 2023
    6. Treatment Of Frontal Fibrosing Alopecia Dermatologic Therapy · 2023
    7. Use of Facial Care Products and Frontal Fibrosing Alopecia: Coincidence or True Association? The Journal of Dermatology · 2021
    8. Frontal Fibrosing Alopecia: An Example of Disrupted Aryl Hydrocarbon Receptor-Mediated Immunological Homeostasis in the Skin? Clinical, cosmetic and investigational dermatology · 2020
    9. Medical Therapy for Frontal Fibrosing Alopecia: A Review and Clinical Approach Journal of The American Academy of Dermatology · 2019
    10. Frontal Fibrosing Alopecia: Efficacy of Treatment Modalities International Journal of Women's Health · 2019
    11. Algorithmic Approach to the Treatment of Frontal Fibrosing Alopecia: A Systematic Review Journal of The American Academy of Dermatology · 2018
    12. Frontal Fibrosing Alopecia in Men: Presentations in 12 Cases and a Review of the Literature Actas Dermo-Sifiliográficas · 2016
    13. Treatment of Frontal Fibrosing Alopecia and Lichen Planopilaris: A Systematic Review Journal of the European Academy of Dermatology and Venereology · 2013
    14. Frontal Fibrosing Alopecia Versus Lichen Planopilaris: A Clinicopathological Study International Journal of Dermatology · 2006
    15. Postmenopausal Frontal Fibrosing Alopecia Archives of Dermatology · 1994