A Novel Type II Cytokeratin, mK6irs, Is Expressed in the Huxley and Henle Layers of the Mouse Inner Root Sheath

    March 2001 in “ Journal of Investigative Dermatology ”
    Noriaki Aoki, S. Sawada, Yutaka Shimomura … Jürgen Schweizer
    Studysummary This study identified a new cytokeratin, mK6irs, specifically expressed in the inner root sheath of mouse hair follicles, distinguishing it as a member of the type II cytokeratin family.
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    Research cited in this study 23

    1. Characterization of a 300 Kbp Region of Human DNA Containing the Type II Hair Keratin Gene Domain Journal of Investigative Dermatology · 2000
    2. Two Different Mutations in the Same Codon of a Type II Hair Keratin (hHb6) in Patients with Monilethrix Journal of Investigative Dermatology · 1999
    3. Identification of Novel Mutations in Basic Hair Keratins hHb1 and hHb6 in Monilethrix: Implications for Protein Structure and Clinical Phenotype Journal of Investigative Dermatology · 1999
    4. A Novel Human Type II Cytokeratin, K6hf, Specifically Expressed in the Companion Layer of the Hair Follicle ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 1998
    5. Onset of Keratin 17 Expression Coincides with the Definition of Major Epithelial Lineages During Skin Development The Journal of Cell Biology · 1998
    6. Monilethrix: A Keratin HHb6 Mutation Is Co-Dominant With Variable Expression Experimental Dermatology · 1998
    7. A Splice Site Mutation in the Human Type I Hair Keratin Gene hHa1 Results in the Expression of a Tailless Keratin Isoform Journal of Biological Chemistry · 1997
    8. Isolation and Characterization of Mouse High-Glycine/Tyrosine Proteins Journal of Biological Chemistry · 1997
    9. Mutations in the Hair Cortex Keratin HHB6 Cause the Inherited Hair Disease Monilethrix Nature Genetics · 1997
    10. Keratin 17 Gene Expression During the Murine Hair Cycle Journal of Investigative Dermatology · 1997
    11. The Role of Keratin Proteins and Their Genes in the Growth, Structure, and Properties of Hair Birkhäuser Basel eBooks · 1997
    12. Formation and Structure of Human Hair Birkhäuser Basel eBooks · 1995
    13. Genetic Disorders of Keratin: Are Scarring Alopecias a Sub-Set? Journal of Dermatological Science · 1994
    14. Solid Basal Cell Epithelioma Possibly Originates From the Outer Root Sheath of the Hair Follicle PubMed · 1993
    15. Histochemistry of the Human Hair Follicle with Consideration of Anagen Phases I to VI Acta Histochemica · 1992
    16. Keratins 1 and 10 as Regular Constituents of Inner Root Sheath and Cuticle Cells in the Human Hair Follicle PubMed · 1990
    17. Cyclic Hair Loss and Regrowth in Transgenic Mice Overexpressing an Intermediate Filament Gene The EMBO Journal · 1990
    18. Expression of Keratin K14 in the Epidermis and Hair Follicle: Insights Into Complex Programs of Differentiation The Journal of Cell Biology · 1989
    19. A New Look Into an Old Problem: Keratins as Tools to Investigate Determination, Morphogenesis, and Differentiation in Skin Genes & Development · 1989
    20. Patterns of Expression of Trichocytic and Epithelial Cytokeratins in Mammalian Tissues: Human and Bovine Hair Follicles Differentiation · 1988
    21. Keratins of the Human Hair Follicle: Hyperproliferative Keratins Consistently Expressed in Outer Root Sheath Cells In Vivo and In Vitro Differentiation · 1987
    22. Acidic and Basic Hair/Nail (Hard) Keratins: Their Colocalization in Upper Cortical and Cuticle Cells of the Human Hair Follicle and Their Relationship to Soft Keratins ˜The œjournal of cell biology/˜The œJournal of cell biology · 1986
    23. The Complement of Native Alpha-Keratin Polypeptides of Hair-Forming Cells: A Subset of Eight Polypeptides That Differ from Epithelial Cytokeratins Differentiation · 1986