Efficacy of Human Foreskin Fibroblast-Conditioned Medium in the Treatment of Androgenic Alopecia: A Pilot Trial

This pilot trial evaluated the efficacy of human foreskin fibroblast-conditioned medium (HFF–CM) in treating androgenic alopecia (AGA) in 14 adults. The study involved four sessions of HFF–CM injections and found significant improvements in hair thickness, density, and dermal density, particularly in females, with no adverse effects reported. The HFF-CM contained growth factors like IGF-1 and KGF/FGF-7, which may contribute to its effectiveness. Despite the small sample size and lack of a control group, the results suggest that HFF-CM could be a promising alternative treatment for AGA, warranting further large-scale studies.