Clinical trial and in vitro study investigating topical application of Zataria multiflora Boiss. and Matricaria chamomilla extracts for androgenetic alopecia
January 2017
in “Cogent Medicine”
TLDR
Extracts improve hair growth in alopecia.
A study investigated the potential of Zataria multiflora Boiss. and Matricaria chamomilla extracts for treating androgenetic alopecia. In vitro tests showed that both extracts had 5α-reductase inhibitory activity. A randomized controlled trial with 60 participants was conducted to validate the in vitro results. The participants were divided into three groups: two groups were treated with the extracts, and the third group received a placebo. All groups also underwent treatment with 5% topical minoxidil twice a day. The study found that the extracts had a positive effect on hair growth, as measured by the size of patches, total number of grown hair, and number of terminal hair. The study suggests that these extracts may be a promising treatment option for androgenetic alopecia.
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