The Human Skin Microbiome in Selected Cutaneous Diseases

New ways to treat acne are being discovered.

This review discusses the role of gut microbiota in autoimmune and immune-mediated dermatological conditions like lupus and psoriasis, but reports no new clinical results; the authors emphasize the need for further study into microbial signatures and treatments.

In this randomized double-blind study, 160 adults with alopecia areata showed significant improvements in hair loss severity after using a bioactive peptide cosmetic product that mimics platelet-rich plasma, while the placebo group showed no significant change, underlining the treatment's potential effectiveness.

In this case report, an 86-year-old man experienced new hair growth and color change in alopecia areata after receiving fecal microbiota transplantation for noninfectious diarrhea.

This review discusses the mechanisms behind alopecia areata and primary cicatricial alopecia and reports no new clinical results, aiming to guide the development of targeted treatments.

This review explores the hair follicle microbiome's interaction with the immune system, discussing its potential clinical implications for scalp health and disease but reports no new clinical results.

This study observed a microbial shift on the scalp of Alopecia areata patients, characterized by an increase in Propionibacterium acnes and a decrease in Staphylococcus epidermidis, compared to healthy controls.

This review discusses genetic and environmental factors contributing to autoimmunity in alopecia areata and reports no new clinical findings, emphasizing the need for further study on its aetiology and pathophysiology.

This review discusses the role of the skin microbiome in maintaining health and modulating atopic dermatitis, emphasizing the need for novel therapeutic strategies, but reports no new clinical results.

This article reviews the epidemiology, clinical evaluation, and pathogenesis of alopecia areata and highlights recent advancements, but it does not report new clinical findings.

This review discusses various sampling methods for studying Propionibacterium acnes in skin follicles and reports no new experimental results; the authors evaluate these methods' strengths and limitations.

This review examines dandruff and seborrheic dermatitis, highlighting the role of Malassezia yeasts in inflammation and hyper-proliferation, and reports no new clinical findings.

This review discusses gender-linked skin differences, such as hormone metabolism and sebum production, and reports no new findings; it suggests these insights might inform male-specific dermatological treatments or cosmetic products.

This review discusses the roles of sebaceous gland activity, Malassezia yeast, and individual susceptibility in scalp flaking disorders, including dandruff and seborrheic dermatitis, but reports no new experiment results.