Optimizing Scalp Cooling: Structural Follicular Characteristics and Restorative Advances

June 2025 in “ Cancer Management and Research ”

Doerthe Schaffrin-Nabe, Anke Josten-Nabe, Adrian Heinze, Andrea Tannapfel, Merle Schaffrin, R. Voigtmann

scalp cooling chemotherapy-induced alopecia hair shaft surface integrity alopecia-inducing medications neutrophil counts real-time shaft monitoring restorative interventions antioxidant therapies cell cycle arrest agents palbociclib

Studysummary This study found that scalp cooling resulted in visible hair retention in 53% of breast cancer patients undergoing Epirubicin/Cyclophosphamide and Paclitaxel treatment, with factors like hair bulb diameter, shaft diameter, and anagen rate significantly predicting outcomes.

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