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    A Prospective Randomized Trial Comparing Low Dose Flutamide, Finasteride, Ketoconazole, and Cyproterone Acetate-Estrogen Regimens in the Treatment of Hirsutism

    Stefano Venturoli, Ombretta Marescalchi, Fabio Colombo … Carlo Flamigni
    Studysummary This study found that all four treatments—flutamide, finasteride, ketoconazole, and EE-CPA—significantly reduced hirsutism, but EE-CPA and flutamide appeared most effective, with varying effects on androgen levels and side-effect profiles.
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    Research cited in this study 13

    1. Comparison of Finasteride Versus Spironolactone in the Treatment of Idiopathic Hirsutism Fertility and Sterility · 1997
    2. Outcome of Long-Term Treatment with the 5α-Reductase Inhibitor Finasteride in Idiopathic Hirsutism: Clinical and Hormonal Effects During a 1-Year Course of Therapy and 1-Year Follow-Up Fertility and Sterility · 1996
    3. Finasteride in the Treatment of Hirsutism: New Therapeutic Perspectives Fertility and Sterility · 1996
    4. Clinical Efficacy and Safety of Low-Dose Flutamide Alone and Combined with an Oral Contraceptive for the Treatment of Idiopathic Hirsutism Clinical endocrinology · 1995
    5. Clinical and Endocrine Effects of Finasteride, a 5α-Reductase Inhibitor, in Women with Idiopathic Hirsutism Fertility and Sterility · 1995
    6. Treatment of Hirsutism with Flutamide and a Low-Dosage Oral Contraceptive in Polycystic Ovarian Disease Patients Fertility and sterility · 1994
    7. Comparison of Flutamide and Spironolactone in the Treatment of Hirsutism: A Randomized Controlled Trial Fertility and Sterility · 1994
    8. Flutamide in the Treatment of Hirsutism International journal of gynaecology and obstetrics · 1991
    9. Cyproterone Acetate for Severe Hirsutism: Results of a Double-Blind Dose-Ranging Study Clinical endocrinology · 1991
    10. Ketoconazole Therapy for Women with Acne and/or Hirsutism ˜The œJournal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism · 1990
    11. The Hair Cycle on the Human Thigh and Upper Arm British journal of dermatology/British journal of dermatology, Supplement · 1985
    12. A Novel Use of Spironolactone: Treatment of Hirsutism ˜The œJournal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism · 1980
    13. Use of Cyproterone Acetate in the Treatment of Acne, Hirsutism, and Virilism Journal of Steroid Biochemistry · 1975

    Related research 7

    1. Medical Treatment Regimens of Hirsutism Reproductive biomedicine online · 2004
    2. Anti-Androgens for the Treatment of Hirsutism Expert opinion on investigational drugs · 2002
    3. A Prospective Randomized Trial Comparing Low Dose Flutamide, Finasteride, Ketoconazole, and Cyproterone Acetate-Estrogen Regimens in the Treatment of Hirsutism The Journal of Clinical Endocrinology and Metabolism · 1999
    4. A Prospective Randomized Trial Comparing Low Dose Flutamide, Finasteride, Ketoconazole, and Cyproterone Acetate-Estrogen Regimens in the Treatment of Hirsutism The Journal of Clinical Endocrinology and Metabolism · 1999
    5. Treatment of Hirsutism: Comparisons Between Different Antiandrogens with Central and Peripheral Effects Fertility and sterility · 1999
    6. Current Aspects of Antiandrogen Therapy in Women Current Pharmaceutical Design · 1999
    7. Hirsutism II: Treatment Australasian journal of dermatology · 1998