Flutamide in the Treatment of Hirsutism

    October 1991 in “ International journal of gynaecology and obstetrics ”
    Tiziano Motta, Giovanni Maggi, Maria Teresa Perra, E. Azzolari, S Casazza, A D’Alberton
    TLDR Flutamide effectively reduces hair growth in women with hirsutism and improves acne and seborrhea without side effects.
    In a study conducted by T. Motta and colleagues, ten hirsute women were treated with flutamide (250 mg/day) for 6 months to assess its efficacy. The treatment significantly reduced hair growth as measured by the Ferriman and Gallwey hair score (P < 0.01). Additionally, there was a notable increase in serum androstenedione levels (P < 0.01), and marked improvements in acne and seborrhea were observed. No side effects were reported during the treatment period. The findings suggested that flutamide's antiandrogenic properties made it a suitable single agent for treating hirsutism.
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