Pyrilutamide vs Topical Finasteride
    10/25/2025

    From the encyclopedia
    Pyrilutamide →

    Experimental topical anti-androgen, also known as KX-826

    Finasteride →

    Popular 5-alpha reductase inhibitor that lowers DHT, taken as a pill or used topically

    At a glance
    In this question or advice post, the primary subjects mentioned are
    💧 Pyrilutamide (topical)
    💧 Finasteride (topical)
    the tone is 😐 neutral with Topical finasteride is currently more effective than pyrilutamide results.

    Other terms

    Topical finasteride is currently more effective than pyrilutamide for hair loss. Combining treatments like topical finasteride and pyrilutamide may enhance results due to different mechanisms.
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      in Chat  12 upvotes 5 months ago
      Topical spironolactone is discussed as a hair loss treatment, with concerns about its effectiveness and side effects compared to finasteride and minoxidil. Users mention its unpleasant smell, potential systemic absorption, and suggest alternatives like pyrilutamide and alfatradiol.

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       40 upvotes 10 months ago
      Dutasteride, finasteride, and minoxidil are considered the top hair loss treatments. Other suggested treatments include Nizoral shampoo, tretinoin, pyrilutamide, zinc, biotin, and low light laser therapy, though opinions on their effectiveness vary.

      community Ultimate Non-5AR (fin/dut) stack?

      in Treatment  1 upvotes 1 year ago
      The conversation discusses alternatives to 5AR inhibitors for hair loss treatment, suggesting options like minoxidil, KX-826, pyrilutimide, microneedling, and topical bicalutamide. Concerns about side effects and the effectiveness of these treatments are also highlighted.

      community Finasteride stopped working, I'm switching to oral Dutasteride

       69 upvotes 1 year ago
      The user switched from Finasteride to topical Dutasteride, Pyrilutamide, and Minoxidil due to hair loss, then decided to switch to oral Dutasteride because of pregnancy concerns. They are considering the frequency of oral Dutasteride use, with suggestions of using it a few times a week for better results and fewer side effects.

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