Shh Gene Regulates Proliferation and Apoptosis of Dermal Papilla Cells in Secondary Hair Follicle Growth Cycle of Cashmere Goats

    July 2024 in “ Animals ”
    Junjie Zhang, Yujing Liu, Jiale Chang … Hong‐Mei Xiao
    Studysummary In this study, the researchers observed that higher expression of the Sonic hedgehog gene in cashmere goats' hair follicle cycles is associated with increased cell proliferation and reduced apoptosis, suggesting its role in enhancing cashmere quality.
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    Research cited in this study 14

    1. Metabolomics Reveals Metabolites Associated with Hair Follicle Cycle in Cashmere Goats BMC veterinary research · 2024
    2. Morphogenesis, Growth Cycle, and Molecular Regulation of Hair Follicles Frontiers in Cell and Developmental Biology · 2022
    3. A Systematic Summary of Survival and Death Signaling During the Life of Hair Follicle Stem Cells Stem Cell Research & Therapy · 2021
    4. Dermal Exosomes Containing miR-218-5p Promote Hair Regeneration by Regulating β-Catenin Signaling Science Advances · 2020
    5. Cell Types Promoting Goosebumps Form a Niche to Regulate Hair Follicle Stem Cells Cell · 2020
    6. Maintaining Hair Inductivity in Human Dermal Papilla Cells: A Review of Effective Methods Skin Pharmacology and Physiology · 2020
    7. Roles of the Hedgehog Signaling Pathway in Epidermal and Hair Follicle Development, Homeostasis, and Cancer Journal of developmental biology · 2017
    8. Shh Maintains Dermal Papilla Identity and Hair Morphogenesis via a Noggin–Shh Regulatory Loop Genes & Development · 2012
    9. The Hair Follicle as a Dynamic Mini-Organ Current Biology · 2009
    10. Embryonic Hair Follicle Fate Change by Augmented Beta-Catenin Through Shh and Bmp Signaling Development · 2009
    11. Molecular Biology of Hair Morphogenesis: Development and Cycling Journal Of Experimental Zoology Part B: Molecular And Developmental Evolution · 2003
    12. Conditional Disruption of Hedgehog Signaling Pathway Defines Its Critical Role in Hair Development and Regeneration Journal of Investigative Dermatology · 2000
    13. Induction of the Hair Growth Phase in Postnatal Mice by Localized Transient Expression of Sonic Hedgehog Journal of Clinical Investigation · 1999
    14. Growth Factors in Hair Organ Development and the Hair Growth Cycle Dermatologic Clinics · 1996

    Related research 3

    1. Single-Cell Sequencing Reveals the Intermediate Cell State and Function of Dermal Papilla Cells in the Hair Follicle Cycle of Cashmere Goats Research Square (Research Square) · 2020
    2. Prolactin and Its Receptor Are Expressed in Murine Hair Follicle Epithelium, Show Hair Cycle-Dependent Expression, and Induce Catagen American Journal of Pathology · 2003
    3. An Estrogen Receptor Pathway Regulates the Telogen-Anagen Hair Follicle Transition and Influences Epidermal Cell Proliferation Proceedings of the National Academy of Sciences of the United States of America · 1996