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    GlossarySmoothened Receptor (SMO)

    protein involved in Hedgehog signaling pathway for cell growth

    The Smoothened Receptor (SMO) is a protein that plays a crucial role in the Hedgehog signaling pathway, which is important for regulating cell growth and development. When activated, SMO helps transmit signals from the cell surface to the inside of the cell, influencing processes like tissue patterning and stem cell maintenance. Malfunctions in this pathway can lead to developmental disorders and cancers.

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      An essential vasodilator with some anti-androgenic effects, has excellent safety record
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      community My hair stopped falling out after I quit smoking

      in Update  60 upvotes 2 weeks ago
      Quitting smoking led to reduced hair loss for the original poster, who also used finasteride and topical minoxidil. Other users shared mixed experiences with smoking and hair loss, with some noticing improvements after quitting and others seeing no change.

      community Quit vaping/smoking = 80% less loss

      in Research/Science  235 upvotes 9 months ago
      Quitting vaping significantly reduced hair loss for a user who was a heavy vaper and also taking finasteride. Some participants suggest nicotine's vasoconstrictive properties may worsen hair loss, while others share personal anecdotes of hair improvement after quitting smoking or vaping.