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    Glossary Sonic hedgehog

    protein crucial for tissue growth and hair follicle development

    Sonic hedgehog (SHH) is a protein that plays a crucial role in regulating the growth and development of various tissues and organs in the body, including hair follicles. It is part of the hedgehog signaling pathway, which is essential for cell differentiation and tissue patterning during embryonic development. Mutations or disruptions in the SHH pathway can lead to developmental disorders and diseases.

    Research 10 of 1000+

    1. Effect of Adenovirus-Mediated Expression of Sonic Hedgehog Gene on Hair Regrowth in Mice With Chemotherapy-Induced Alopecia JNCI: Journal of the National Cancer Institute · 2001 · 39 citations
    2. Analysis of Sonic Hedgehog signalling pathway gene expression in Basal Cell Carcinoma and in GLII induced systems Queen Mary Research Online (Queen Mary University of London) · 2007
    3. Gene and tonic: Sonic hedgehog disruption and fetal alcohol syndrome Reproductive Toxicology · 2011
    4. Hair follicles’ transit-amplifying cells govern concurrent dermal adipocyte production through Sonic Hedgehog Genes & Development · 2016 · 75 citations
    5. 708 Polycomb-mediated repression and Sonic hedgehog signaling regulate Merkel cell specification Journal of Investigative Dermatology · 2016
    6. Induction of the hair growth phase in postnatal mice by localized transient expression of Sonic hedgehog Journal of Clinical Investigation · 1999 · 231 citations
    7. Transient agonism of the sonic hedgehog pathway triggers a permanent transition of skin appendage fate in the chicken embryo Science Advances · 2023 · 18 citations
    8. Hair growth-promoting effect of recombinant human sonic hedgehog proteins Biomedical dermatology · 2019 · 3 citations
    9. Shh Gene Regulates the Proliferation and Apoptosis of Dermal Papilla Cells to Affect Its Differential Expression in Secondary Hair Follicle Growth Cycle of Cashmere Goats Animals · 2024 · 7 citations
    10. Hedgehog signalling in skin development and cancer Experimental Dermatology · 2006 · 190 citations
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    1. New study suggests hair regrowth on wounded and bald skin may be possible Reddit · 1 Dec 2018

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