Anti-Hair Loss Potential of Acanthus Ebracteatus (Sea Holly) in Cell Culture Assays and an Open-Label, Non-Comparative Clinical Trial

    August 2026 in “ Revista Brasileira de Farmacognosia ”
    Puxvadee Chaikul, Nattita Junsawat, Mayuree Kanlayavattanakul, Nattaya Lourith
    Studysummary Sea holly extract may help reduce hair loss.
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    Research cited in this study 18

    1. Effect of Plantago Asiatica L. Extract on the Anagen Phase in Human Hair Follicle Dermal Papilla Cells Journal of Cosmetic Dermatology · 2023
    2. Assessment of the Anti-Hair Loss Potential of Camellia Japonica Fruit Shell Extract In Vitro International Journal of Cosmetic Science · 2022
    3. Is Dutasteride a Therapeutic Alternative for Amyotrophic Lateral Sclerosis? Biomedicines · 2022
    4. Hair Regeneration Effects of Lespedeza Bicolor Extract In Vivo and In Vitro Applied sciences · 2022
    5. Effects of Acanthus Ebracteatus Vahl Extract and Verbascoside on Human Dermal Papilla and Murine Macrophage Scientific Reports · 2022
    6. Health-Related Quality of Life, Depression, and Self-Esteem in Patients With Androgenetic Alopecia JAMA Dermatology · 2021
    7. Para Rubber Seed Oil: The Safe and Efficient Bio-Material for Hair Loss Treatment Journal of cosmetic dermatology · 2020
    8. Repurposing Kir6/SUR2 Channel Activator Minoxidil to Arrest Growth of Gynecologic Cancers Frontiers in pharmacology · 2020
    9. Minoxidil And Its Use In Hair Disorders: A Review Drug Design Development and Therapy · 2019
    10. An Overview of Herbal Alternatives in Androgenetic Alopecia Journal of Cosmetic Dermatology · 2019
    11. Review of Hair Follicle Dermal Papilla Cells as In Vitro Screening Model for Hair Growth International Journal of Cosmetic Science · 2018
    12. Androgenetic Alopecia: A Review Endocrine · 2017
    13. Novel ALK5 Inhibitor TP0427736 Reduces TGF-β Induced Growth Inhibition in Human Outer Root Sheath Cells and Elongates Anagen Phase in Mouse Hair Follicles Pharmacological Reports · 2017
    14. The Impact of Oxidative Stress on Hair International Journal of Cosmetic Science · 2015
    15. A Hairy Fall: Syncope Resulting from Topical Application of Minoxidil Case Reports · 2015
    16. Resting No More: Redefining Telogen, the Maintenance Stage of the Hair Growth Cycle Biological Reviews · 2014
    17. The Effect of Autologous Activated Platelet Rich Plasma Injection on Pattern Hair Loss: Clinical and Histomorphometric Evaluation BioMed Research International · 2014
    18. Standardizing the 60-Second Hair Count Archives of Dermatology · 2008