Sulfotransferase Activity in Plucked Hair Follicles Predicts Response to Topical Minoxidil in the Treatment of Female Androgenetic Alopecia

    April 2014 in “ Dermatologic Therapy ”
    Janet L. Roberts, Nisha Desai, John D. McCoy, Andy Goren
    Studysummary This study reported that sulfotransferase activity in plucked hair follicles can predict treatment response to 5% topical minoxidil in women with androgenetic alopecia with high sensitivity and specificity.
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    Research cited in this study 9

    1. Interventions for Female Pattern Hair Loss Cochrane Database of Systematic Reviews · 2012
    2. A Multicenter, Randomized, Placebo-Controlled, Double-Blind Clinical Trial of a Novel Formulation of 5% Minoxidil Topical Foam Versus Placebo in the Treatment of Androgenetic Alopecia in Men Journal of The American Academy of Dermatology · 2007
    3. A Randomized, Placebo-Controlled Trial of 5% and 2% Topical Minoxidil Solutions in the Treatment of Female Pattern Hair Loss Journal of The American Academy of Dermatology · 2004
    4. Sulfation of Minoxidil by Multiple Human Cytosolic Sulfotransferases Chemico-Biological Interactions · 1998
    5. Diffuse Hypertrichosis During Treatment with 5% Topical Minoxidil British Journal of Dermatology · 1997
    6. Androgenetic Alopecia in the Female Archives of Dermatology · 1994
    7. Minoxidil Sulfation in the Hair Follicle Skin Pharmacology and Physiology · 1994
    8. Use of Topical Minoxidil Therapy for Androgenetic Alopecia in Women International Journal of Dermatology · 1993
    9. Minoxidil Sulfate Is the Active Metabolite That Stimulates Hair Follicles Journal of Investigative Dermatology · 1990