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3 / 3 resultslearn Osteopontin
signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss
learn Tretinoin
the gold standard retinoid in dermatology that's also helpful for hair regrowth alongside Minoxidil
Research
5 / 312 results
research Sulfotransferase Activity in Plucked Hair Follicles Predicts Response to Topical Minoxidil Treatment in Brazilian Female Pattern Hair Loss Patients
Hair enzyme activity predicts minoxidil success in Brazilian women with hair loss.

research Sulfotransferase SULT1A1 Activity in Hair Follicle: A Prognostic Marker of Response to Minoxidil Treatment in Androgenetic Alopecia
Sulfotransferase SULT1A1 activity may predict minoxidil treatment success for hair loss.

research Characterization of Follicular Minoxidil Sulfotransferase Activity in a Cohort of Pattern Hair Loss Patients from the Indian Subcontinent
About 41% of Indian hair loss patients have low enzyme activity that affects hair loss treatment effectiveness, with men affected more than women. Testing for this can guide treatment.

research Novel Topical Booster Enhances Follicular Sulfotransferase Activity in Patients with Androgenetic Alopecia: A New Strategy to Improve Minoxidil Response
Topical booster improves hair loss treatment effectiveness.

research Hair Follicle Sulfotransferase Activity and Effectiveness of Oral Minoxidil in Androgenetic Alopecia
Low SULT activity in hair follicles leads to better response to oral minoxidil for hair loss.
Community Join
5 / 216 resultscommunity Minoxidil + Tretinoin if you suspect you have low sulfotransferase enzyme activity
Minoxidil may not be effective due to low sulfotransferase activity, and the user considers adding tretinoin to the regimen. They are unsure about the timing and combination with microneedling.
community Tretinoin vs. micro-needling: what increases sulfotransferase activity more?
Tretinoin and microneedling both enhance hair growth through different mechanisms, with microneedling being considered safe for long-term use. Optimal microneedling needle length varies, but 0.8 mm is suggested for hair growth, and a Dermastamp is recommended to avoid skin damage.
community Minoxidil Non-responders: Have you tried Minoxidil Sulfate?
Minoxidil non-responders may benefit from using minoxidil sulfate due to reduced sulfotransferase activity in their scalps. Users are encouraged to share their experiences with minoxidil sulfate.
community You may not have the enzyme for topical minoxidil to work - a rarely talked about impact
Some people may not respond to topical minoxidil due to low SULT1A1 enzyme activity, but oral minoxidil can be effective. Tretinoin may enhance minoxidil's effectiveness, and some users prefer oral minoxidil despite side effects.

community Minoxidil Response Bottlenecks: Why Sulfation and Transport Matter (And Where Tretinoin Fits In)
Minoxidil's effectiveness is limited by the need for sulfation and proper transport to hair follicles, with tretinoin potentially enhancing its effects by promoting enzyme activity and keratinocyte differentiation. Tretinoin may improve minoxidil's response by boosting the expression of necessary enzymes and transporters.