Gradient-Dependent Release of the Model Drug TRITC-Dextran from FITC-Labeled BSA Hydrogel Nanocarriers in the Hair Follicles of Porcine Ear Skin

    October 2016 in “ European Journal of Pharmaceutics and Biopharmaceutics ”
    Ngo Bich Nga Nathalie Tran, Fanny Knorr, Wing Cheung Mak … Alexa Patzelt
    Studysummary In this study, FITC-labeled BSA nanocarriers delivered a model drug deeper into porcine ear skin hair follicles than the carriers themselves, as shown by confocal microscopy.
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    Research cited in this study 6

    1. Triggered Release of Model Drug from Gold Nanoparticle-Doped Bovine Serum Albumin Nanocarriers in Hair Follicles Using Infrared A Radiation Acta Biomaterialia · 2015
    2. Triggering of Drug Release of Particles in Hair Follicles Journal of controlled release · 2012
    3. Selective Follicular Targeting by Modification of the Particle Sizes Journal of Controlled Release · 2011
    4. The Role of Hair Follicles in the Percutaneous Absorption of Caffeine BJCP. British journal of clinical pharmacology/British journal of clinical pharmacology · 2007
    5. 40nm, But Not 750 or 1,500nm, Nanoparticles Enter Epidermal CD1a+ Cells After Transcutaneous Application on Human Skin ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2006
    6. Transfollicular Drug Delivery: Is It a Reality? International journal of pharmaceutics · 2005