Genome-Wide DNA Methylation and Transcriptome Analyses Reveal the Key Gene for Wool Type Variation in Sheep

July 2023 in “ Journal of Animal Science and Biotechnology ”

Jiankui Wang, Guoying Hua, Ganxian Cai, Yuhao Ma, Xue Yang, Letian Zhang, Rui Li, Jianbin Liu, Qing Ma, Keliang Wu, Yaofeng Zhao, Xuemei Deng

DNA methylation transcriptome analyses SOSTDC1 gene dermal papilla epigenetic modification

Studysummary This study discovered that lambs with coarse, ancestral-like wool in a population of modern fine wool sheep exhibited overexpression of the SOSTDC1 gene, linked to epigenetic changes, which helps understand the development and diversification of wool types in sheep breeding.

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