Efficacy of Thermus Thermophilus Fermentation Extract in Promoting Hair Growth and Improving Scalp Health in Androgenic Alopecia: A Clinical and In Vitro Study

    March 2025 in “ Journal of Cosmetic Dermatology ”
    Yudong Hu, Zeyu Wei, Xiaogang Wu … Sophia Yi Zhang
    Studysummary This study explored the effects of TTFE on male androgenic alopecia, finding that topical application increased hair density, follicular diameter, and scalp hydration while reducing water loss and sebum production in a 12-week trial.
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    Research cited in this study 12

    1. Finasteride for Hair Loss: A Review Journal of Dermatological Treatment · 2021
    2. Deciphering the Molecular Morphology of the Human Hair Cycle: Wnt Signalling During the Telogen–Anagen Transformation British Journal of Dermatology · 2019
    3. Reversing Wrinkled Skin and Hair Loss in Mice by Restoring Mitochondrial Function Cell death and disease · 2018
    4. Changes in the Sebaceous Gland in Patients with Male Pattern Hair Loss (Androgenic Alopecia) Journal of Cosmetic Dermatology · 2015
    5. Depressive Symptoms and Suicidal Thoughts Among Former Users of Finasteride With Persistent Sexual Side Effects The Journal of Clinical Psychiatry · 2012
    6. Hair Cycle Resting Phase Is Regulated by Cyclic Epithelial FGF18 Signaling Journal of Investigative Dermatology · 2012
    7. Review of Hair Follicle Dermal Cells Journal of Dermatological Science · 2009
    8. Minoxidil: Mechanisms of Action on Hair Growth British Journal of Dermatology · 2004
    9. Molecular Mechanisms of Androgenetic Alopecia Experimental Gerontology · 2002
    10. Molecular Mechanisms Regulating Hair Follicle Development ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2002
    11. The Biology of Hair Follicles The New England Journal of Medicine · 1999
    12. Cellular And Developmental Aspects Of Androgenetic Alopecia Experimental Dermatology · 1998

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    5. Towards a Molecular Understanding of Hair Loss and Its Treatment Trends in Molecular Medicine · 2001