Keratin 15 Promotes a Progenitor Cell State in Basal Keratinocytes of Skin Epidermis

    December 2025 in “ The Journal of Cell Biology ”
    Catherine J. Redmond, Sarah Steiner, Erez Cohen … Pierre A. Coulombe
    Studysummary This study found that keratin 15 lacks the ability to sequester YAP1 in keratinocytes effectively, unlike keratin 14, and suggests that a higher K15:K14 ratio may promote a progenitor state and inhibit differentiation in epidermal keratinocytes.
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    Research cited in this study 16

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