June 201519
Combined oral finasteride and topical minoxidil improved hair in 94% of men, outperforming either treatment alone. Atherogenic index in women with early-onset pattern hair loss showed worse cholesterol profiles and higher cardiovascular risk markers. In mice, Wnt1a-maintained dermal papilla cells regenerated hair in a 3D culture system, and topical oleuropein induced anagen growth through Wnt10b/β-catenin signaling.
- Combined treatment with oral finasteride and topical minoxidil in male androgenetic alopecia: a randomized and comparative study in Chinese patients In 450 Chinese men, combining oral finasteride with 5% topical minoxidil improved hair in 94% — better than finasteride (80.5%) or minoxidil (59%) alone.
- Wnt1a maintains characteristics of dermal papilla cells that induce mouse hair regeneration in a 3D preculture system A 3D collagen-chitosan culture with Wnt1a-maintained dermal papilla cells regenerated hair in nude mice, a possible route to cell-based hair loss treatment.
- Atherogenic index of plasma in non-obese women with androgenetic alopecia Non-obese women with early-onset pattern hair loss had worse cholesterol profiles and higher cardiovascular risk markers than matched controls.
- Topical Application of Oleuropein Induces Anagen Hair Growth in Telogen Mouse Skin Topical oleuropein, an olive compound, induced hair growth in mice by activating Wnt10b/β-catenin signaling and growth factors in skin.
- Female pattern alopecia and telogen effuvium: figuring out diffuse alopecia A review on distinguishing female pattern hair loss from telogen effluvium when women present with diffuse thinning.
- Hair transplantation update A review of modern hair transplant techniques (strip harvesting and FUE) for male and female pattern hair loss, recommending medical therapy alongside.
- Cyclic Alopecia and Abnormal Epidermal Cornification in Zdhhc13 -Deficient Mice Reveal the Importance of Palmitoylation in Hair and Skin Differentiation Mice lacking the palmitoylation enzyme DHHC13 develop cyclic alopecia and skin barrier defects from loss of cornifelin.
- Frequency of body dysmorphic disorder among patients with complaints of hair loss Nearly 30% of patients complaining of hair loss — more often men — met criteria for body dysmorphic disorder, ten times the rate in general dermatology patients.
- Imbalance of T‐helper 17 and regulatory T cells in patients with alopecia areata Patients with alopecia areata showed higher Th17 and lower regulatory T-cell levels, correlating with disease activity and duration.
- Methotrexate in Severe Childhood Alopecia Areata: Long-term Follow-up Long-term follow-up of methotrexate treatment in severe childhood alopecia areata.
- Mathematical model for alopecia areata A mathematical model of alopecia areata points to immune privilege guardians and interferon-γ as key drivers of disease dynamics.
- Evaluation of wavelength-dependent hair growth effects on low-level laser therapy: an experimental animal study In rats, 830-nm low-level laser stimulated hair growth more than 632, 670, or 785 nm.
- Topical Calcipotriol Therapy for Mild-to-Moderate Alopecia Areata: A Retrospective Study. In a retrospective study of 48 patients with mild-to-moderate alopecia areata, twice-daily calcipotriol cream produced at least 50% regrowth in 75% after 12 weeks.
- Microneedling dilates the follicular infundibulum and increases transfollicular absorption of liposomal sepia melanin In ex vivo human skin, microneedling widened follicular openings 47% and boosted delivery of liposomal melanin, potentially aiding laser hair removal.
- Biology of the hair follicle and mechanisms of nonscarring and scarring alopecia A review of hair follicle biology and mechanisms behind scarring and nonscarring hair disorders.
- Alopecia areata update A review of alopecia areata presentation, mechanisms, and treatment options, noting no cure or universally proven therapy exists.
- Hair loss in patients with skin of color A review of diagnosing and managing hair loss disorders more common in skin of color, including scarring alopecias and traction alopecia.
- Programming of induced pluripotent stem cells for hair follicle regeneration. Programming induced pluripotent stem cells for hair follicle regeneration.
- Thymosin Beta-4 Induces Mouse Hair Growth