March 201317
A review of hair restoration found FUE gives results comparable to FUT transplantation, and warned against delegating surgery to unlicensed technicians. In one observational study, early-onset frontal baldness in African-American men was associated with higher prostate cancer odds and more aggressive tumors. In a multiethnic veteran cohort, early-onset and frontal balding was associated with higher prostate cancer risk and high-grade disease. In vitro and in rats, iontophoresis-assisted minoxidil sulfate delivery increased follicular uptake up to fivefold, a possible future treatment improvement.
- Relationship of Early-Onset Baldness to Prostate Cancer in African-American Men In 537 African-American men, early-onset frontal baldness was associated with higher prostate cancer odds and more aggressive tumors.
- Androgenetic alopecia at various ages and prostate cancer risk in an equal-access multiethnic case–control series of veterans In a 708-veteran case-control study, early-onset and frontal balding was associated with higher prostate cancer risk and high-grade disease.
- Current Practices and Controversies in Cosmetic Hair Restoration A review finds FUE gives results comparable to the gold-standard FUT transplant, and warns against delegation of surgery to unlicensed technicians.
- Iontophoresis-Targeted, Follicular Delivery of Minoxidil Sulfate for the Treatment of Alopecia In vitro and in rats, iontophoresis increased minoxidil sulfate delivery into hair follicles up to fivefold, a possible future treatment improvement.
- Fabrication of a 3D hair follicle‐like hydrogel by soft lithography Researchers built a 3D hydrogel mimicking hair follicle architecture that supported dermal and epithelial cell growth for 14 days.
- A functional polymorphism in interleukin-1α (IL1A) gene is associated with risk of alopecia areata in Chinese populations In 939 Chinese subjects, an IL1A gene insertion polymorphism was associated with roughly halved risk of alopecia areata.
- Drug delivery to hair follicles A review explains how drug delivery into hair follicles depends on particle properties and vehicles, with nanoparticles and stimuli as promising strategies.
- Treatment of frontal fibrosing alopecia and lichen planopilaris: a systematic review A systematic review of FFA and lichen planopilaris found no proven treatment; oral 5-alpha-reductase inhibitors gave good response in 45% of reported FFA cases.
- Blocking Potassium Channels (Kv1.3): A New Treatment Option for Alopecia Areata? blocking Kv1.3 potassium channels is proposed as a potential new treatment for alopecia areata.
- Evaluación clínica del pelo corporal en una población de mujeres colombianas: determinación del punto de corte para el diagnóstico de hirsutismo In 323 Colombian women, a Ferriman-Gallwey score of 6 or below was proposed as the hirsutism diagnostic cutoff for that population.
- Hopx expression defines a subset of multipotent hair follicle stem cells and a progenitor population primed to give rise to K6+ niche cells In mice, Hopx marks a subset of hair follicle stem cells and progenitors that generate K6+ niche cells regulating stem cell quiescence.
- The regulatory role of the tetrapeptide AcSDKP in skin and hair physiology and the prevention of ageing effects in these tissues – a potential cosmetic role The tetrapeptide AcSDKP stimulated follicle cells and promoted hair shaft elongation in cultured human follicles, suggesting cosmetic potential.
- Ascorbigen Induces Dermal Papilla Cell Proliferation in Vitro , but Fails to Modulate Chemotherapy-Induced Alopecia in Vivo Ascorbigen stimulated dermal papilla cells in vitro but did not protect against chemotherapy-induced alopecia in mice.
- Clinical effects of non-ablative and ablative fractional lasers on various hair disorders: a case series of 17 patients In a 17-patient case series of uncommon hair disorders, fractional lasers produced clinical response in about 70% without notable side effects.
- No genetic support for a contribution of prostaglandins to the aetiology of androgenetic alopecia A GWAS-based candidate-gene analysis found no genetic support for prostaglandin involvement in androgenetic alopecia.
- Analysis of clinical and histologic correlations in alopecia areata and telogen effluvium: adversities in alopecia pattern mimicry. A study of biopsies found alopecia pattern mimics and overlap cases between alopecia areata and telogen effluvium are common and complicate diagnosis.
- [Effect of PRP on the proliferation of dermal papilla cells and hair follicle regeneration in mice]. PRP boosted dermal papilla cell proliferation and hair follicle regeneration in mice, but the paper is not in English.