November 201316
A follicle SULT1A1 enzyme assay predicted minoxidil response in pattern hair loss with 95% sensitivity and 73% specificity. In Taiwanese men, higher body mass index was associated with about 3.5 times higher odds of severe baldness. In children with alopecia areata, clobetasol 0.05% cream reduced hair-loss area more than hydrocortisone 1%. Among breast cancer survivors, recent aromatase inhibitor therapy was linked to roughly 2.5 times higher odds of reported hair loss, based on self-report. In breast cancer patients, chemotherapy caused diffuse hair loss peaking at 6 weeks with regrowth by 3 months after stopping.
- Novel enzymatic assay predicts minoxidil response in the treatment of androgenetic alopecia A preliminary assay of follicle SULT1A1 enzyme activity predicted minoxidil response with 95% sensitivity and 73% specificity.
- Hair cycle control by leptin as a new anagen inducer In mice, leptin injections induced the hair growth phase, identifying leptin as a new anagen inducer working through Stat3 signalling.
- Suppression of eukaryotic initiation factor 4E prevents chemotherapy-induced alopecia In transgenic mice, transiently suppressing the translation factor eIF4E arrested hair-follicle cells in G1 and prevented cyclophosphamide-induced hair loss, suggesting a new prevention strategy.
- Clobetasol Propionate, 0.05%, vs Hydrocortisone, 1%, for Alopecia Areata in Children In a trial of 41 children with alopecia areata, clobetasol 0.05% cream reduced hair-loss area significantly more than hydrocortisone 1% over 24 weeks.
- Higher body mass index is associated with greater severity of alopecia in men with male-pattern androgenetic alopecia in Taiwan: A cross-sectional study In 189 Taiwanese men, overweight or obese men with pattern hair loss had about 3.5 times higher odds of severe baldness.
- Aromatase inhibitor therapy and hair loss among breast cancer survivors In 851 breast cancer survivors, starting aromatase inhibitors within the past 2 years was linked to roughly 2.5 times higher odds of reported hair loss or thinning, based on self-report.
- Analysis of quantitative changes in hair growth during treatment with chemotherapy or tamoxifen in patients with breast cancer: a cohort study In breast cancer patients, chemotherapy caused diffuse hair loss peaking at 6 weeks with regrowth to baseline by 3 months after stopping; tamoxifen did not affect hair.
- Exposure to gamma-rays at the telogen phase of the hair cycle inhibits hair follicle regeneration at the anagen phase in mice In mice, gamma irradiation during the resting phase damaged hair follicle stem cells, reducing follicle density and pigment in the next growth phase.
- Robotic Hair Restoration a review of the ARTAS robotic system for harvesting follicular unit grafts, its capabilities, advantages and disadvantages.
- Ecklonia cava promotes hair growth Ecklonia cava extract elongated human hair shafts in culture and induced the growth phase in mice, apparently via IGF-1.
- Keratin 79 identifies a novel population of migratory epithelial cells that initiates hair canal morphogenesis and regeneration In mice, keratin-79 cells migrate outward from the hair germ to form the hair canal during development and adult regeneration.
- Elastin staining patterns in primary cicatricial alopecia In 58 scarring alopecia biopsies, elastin staining patterns helped distinguish lichen planopilaris from central centrifugal cicatricial alopecia.
- Protection against chemotherapy-induced alopecia: targeting ATP-binding cassette transporters in the hair follicle? A review proposes preventing chemotherapy-induced hair loss by boosting ABC transporter proteins in the follicle with topical receptor agonists.
- Phototrichogram analysis of normal scalp hair characteristics with aging In 1,357 Koreans, scalp hair density declined with age while hair thickness plateaued mid-life and white hair rose after 40.
- Complications in Hair Restoration a review of how surgeon and assistant errors during hair restoration cause unnatural hairlines and recipient-site problems.
- Cutaneous hyperandrogenism: role of antiandrogen therapy in acne, hirsutism, and androgenetic alopecia. a review of antiandrogen therapy for acne, hirsutism and androgenetic alopecia in cutaneous hyperandrogenism.