July 201311
Alopecia areata patients showed higher serum oxidant markers and lower antioxidant capacity than controls, correlating with severity. Chinese black tea extract in mice promoted hair growth, enhanced by capsaicin. Blocking EGFR signaling in mice prevented cyclophosphamide-induced alopecia. Polygonum multiflorum root compounds in lab tests increased dermal papilla cell proliferation and lengthened mouse vibrissa hairs.
- Role for the Epidermal Growth Factor Receptor in Chemotherapy-Induced Alopecia In mice, blocking EGFR signaling with skin-targeted mutation or drugs like erlotinib prevented cyclophosphamide-induced alopecia.
- Investigation of six novel susceptibility loci for male androgenetic alopecia in women with female pattern hair loss Six novel male androgenetic alopecia susceptibility loci were investigated in women with female pattern hair loss.
- Promotion effect of constituents from the root of Polygonum multiflorum on hair growth In lab tests, compounds from Polygonum multiflorum root increased dermal papilla cell proliferation and lengthened mouse vibrissa hairs.
- Oxidative Stress in Alopecia Areata: A Case–Control Study Alopecia areata patients showed significantly higher serum oxidant markers and lower antioxidant capacity than controls, correlating with severity.
- Microarray analysis of androgenetic and senescent alopecia: Comparison of gene expression shows two distinct profiles Microarray comparison of androgenetic and senescent alopecia found two distinct gene expression profiles.
- A Hair Growth-Promoting Effect of Chinese Black Tea Extract in Mice In mice, topical Chinese black tea extract promoted hair growth, synergistically enhanced by capsaicin, possibly via estrogen receptors.
- The association between Interleukin (IL)-4 gene intron 3 VNTR polymorphism and alopecia areata (AA) in Turkish population In a Turkish population, an IL-4 gene intron 3 VNTR polymorphism was associated with alopecia areata susceptibility.
- Tolerance induction by hair-specific keratins in murine alopecia areata In mice, keratins K71 and K31 drive alopecia areata, and soluble peptide vaccination induced T cell anergy that prevented disease progression.
- Ageing and colony-forming efficiency of human hair follicle keratinocytes Ageing reduces the colony-forming efficiency of human hair follicle keratinocytes in a lab clonal assay.
- In Vivo Monitoring of Survival and Proliferation of Hair Stem Cells in a Hair Follicle Generation Animal Model In mice, bioluminescence imaging successfully tracked transplanted hair stem cells noninvasively as they generated new follicles.
- Hair Follicle Transplantation on Scar Tissue In 18 followed cases, hair transplantation into scar tissue gave excellent or good results in 83%, though burn scars fared better than incision scars.