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    Did you mean Steroid Sulfatase Inhibitors?
    GlossarySteroid Sulfatase Inhibitors

    block enzyme activity to reduce active steroid levels

    Steroid Sulfatase Inhibitors (STS inhibitors) are compounds that block the activity of the enzyme steroid sulfatase, which is involved in the conversion of sulfated steroid precursors into active steroids like estrogen. By inhibiting this enzyme, STS inhibitors can reduce the levels of active steroids, potentially offering therapeutic benefits in conditions like hormone-sensitive cancers and certain skin disorders.

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      community Zix + Topical Fin : Blood Test Before/After, AMA and suggestions

      in Treatment  48 upvotes 4 years ago
      A user's plan to use Zix and topical finasteride (5AR inhibitors) for hair loss, followed by blood testing before/after. The user has suggested creating a fund to cover part of the cost of their blood tests. Replies to their post discuss the effectiveness of the treatments.

      community DLQ01: A Better "Minoxidil" PGF2a synthetic analogue.

      in Research/Science  3 upvotes 1 month ago
      DLQ01, a prostaglandin F2α analog, shows promise for hair growth by directly stimulating PGE2/PGF receptors without needing conversion, and can be combined with minoxidil and retinoids like tretinoin for enhanced effectiveness. Minoxidil's efficacy may be reduced by COX-1 inhibitors, but using prostaglandin analogs like Latanoprost or Bimatoprost can help maintain its effectiveness.

      community Why don't Minoxidil regenerated hairs become terminal on the head?

      in Minoxidil  102 upvotes 6 days ago
      Minoxidil helps hair growth by increasing blood flow and prolonging the growth phase, but it doesn't address the root cause of hair loss, such as DHT sensitivity. Finasteride can help maintain some gains by blocking DHT, but stopping Minoxidil often leads to hair loss because the new hairs are dependent on it.

      community He used Dutasteride for 20 years. Interview

      in Treatment  111 upvotes 4 months ago
      Dutasteride has been used for 20 years with some hair thickness improvement but no dramatic regrowth. The user also experimented with minoxidil, tretinoin, and peptides like BPC 157 for potential benefits in hair density and quality.