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GlossarySulfation

biochemical process adding sulfate groups to molecules

Sulfation is a biochemical process where a sulfate group (SO₄) is added to molecules, such as hormones, drugs, or neurotransmitters. This modification often alters the molecule's function, solubility, or how it is metabolized and excreted by the body. In the context of hair biology, sulfation can influence the activity of certain proteins and enzymes involved in hair growth and health.

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Tracking 10 products like 291 BondiBoost, 293 Hair Growth Support Shampoo, 117 REGROWTH LABS M7A TRICHOGEN, 120 REGROWTH LABS D5A and 123 Polaris minoxidil shampoo NR02 from by companies like Amazon and Minoxidil Express. View all 10 products »

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research Sulfotransferases, Sulfatases, and Formylglycine-Generating Enzymes: A Sulfation Fascination

83 citations, July 2008 in “Current Opinion in Chemical Biology”

The document concludes that understanding sulfation biology is crucial for creating treatments due to its importance in biological functions and disease.

research Sulfation of Minoxidil by Human Liver Phenol Sulfotransferase

68 citations, September 1990 in “Biochemical Pharmacology”

Minoxidil activates hair growth by being sulfated by P-PST in the human liver.

research Sulfation of Minoxidil by Liver Sulfotransferase

66 citations, September 1982 in “Biochemical Pharmacology”

Liver enzyme helps minoxidil work better for blood vessel relaxation.

research Sulfation of Minoxidil by Multiple Human Cytosolic Sulfotransferases

59 citations, February 1998 in “Chemico-Biological Interactions”

Minoxidil breakdown varies by enzymes, affecting hair loss treatment effectiveness.

research Enzymatic and Non-Enzymatic Sulfation Mechanisms in the Biological Actions of Minoxidil

53 citations, January 1993 in “Biochemical Pharmacology”

Minoxidil needs activation to work, and minoxidil sulfate helps with hair growth and blood pressure.

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community Minoxidil Sulfate makes everyone a responder

in Research/Science 257 upvotes 2 months ago

Minoxidil sulfate is more effective than regular minoxidil, especially for those with low sulfotransferase levels or scalp sensitivity, but it is unstable unless delivered in a liposomal format. Combining minoxidil with tretinoin can enhance effectiveness, and stopping minoxidil use can lead to rapid hair loss.

community Sugars ARE important for hair growth | Glycosaminoglycans as Hair Growth Stimulant

in Research/Science 80 upvotes 6 months ago

Glycosaminoglycans are important for hair growth, and combining minoxidil with tretinoin and Biopeptide-CL may enhance hair growth by boosting glycosaminoglycan levels and improving the hair follicle environment. Users discussed the potential effectiveness and future of these treatments.

community just saw my hair under harsh sunlight and devastated..

in Chat 121 upvotes 2 months ago

The conversation discusses hair loss struggles and treatments, including oral minoxidil, oral finasteride, and RU58841. Users share experiences and advice, suggesting options like topical minoxidil, microneedling, hair transplants, and scalp micropigmentation.

Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

community Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

in Research 759 upvotes 3 months ago

The treatment for androgenetic alopecia involves using finasteride and minoxidil with intense exercise and cold exposure to boost metabolism and reduce androgenic effects, potentially leading to hair regrowth. This approach may activate biological pathways for improved hair and overall health.

community Peptides that Stop Hair Loss? | In-depth Literature Review Video

in Research/Science 76 upvotes 6 months ago

Peptides like TB500, KPV, GHK-CU, and BPC-157 are overhyped for hair growth with limited proven effectiveness in humans. Combining peptides with delivery methods like iontophoresis and sonophoresis shows promise, but many claims remain unproven.

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